Bunitrolol

Modify Date: 2024-01-08 23:40:29

Bunitrolol Structure
Bunitrolol structure
Common Name Bunitrolol
CAS Number 34915-68-9 Molecular Weight 248.32
Density 1.09g/cm3 Boiling Point 414.2ºC at 760mmHg
Molecular Formula C14H20N2O2 Melting Point N/A
MSDS N/A Flash Point 204.3ºC

 Use of Bunitrolol


Bunitrolol is a beta-adrenergic antagonist. Bunitrolol has intrinsic sympathomimetic activity. Bunitrolol can be used for the research of ischemic myocardium[1].

 Names

Name 2-[3-(tert-butylamino)-2-hydroxypropoxy]benzonitrile
Synonym More Synonyms

 Bunitrolol Biological Activity

Description Bunitrolol is a beta-adrenergic antagonist. Bunitrolol has intrinsic sympathomimetic activity. Bunitrolol can be used for the research of ischemic myocardium[1].
Related Catalog
References

[1]. Chiba K, et al. Effects of bunitrolol on ischemic myocardial energy metabolism in dogs. J Pharm Sci. 1993 Apr;82(4):384-8.

 Chemical & Physical Properties

Density 1.09g/cm3
Boiling Point 414.2ºC at 760mmHg
Molecular Formula C14H20N2O2
Molecular Weight 248.32
Flash Point 204.3ºC
Exact Mass 248.15200
PSA 65.28000
LogP 2.07698

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DI2530000
CHEMICAL NAME :
Benzonitrile, o-(3-(tert-butylamino)-2-hydroxypropoxy)-
CAS REGISTRY NUMBER :
34915-68-9
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H20-N2-O2
MOLECULAR WEIGHT :
248.36
WISWESSER LINE NOTATION :
NCR BO1YQ1MX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
46 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 17,341,1972

 Safety Information

HS Code 2926909090

 Synthetic Route

~%

Bunitrolol Structure

Bunitrolol

CAS#:34915-68-9

Literature: Boehringer Ingelheim GmbH Patent: US3940489 A1, 1976 ;

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2926909090
Summary HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

Bunitrolol
Stresson
Bunitrolol HCl
2-Nitrilo-N-tert-butylphenoxypropanolamine
KO-1366