MES-13d

Modify Date: 2024-01-19 22:13:56

MES-13d Structure
MES-13d structure
Common Name MES-13d
CAS Number 352534-94-2 Molecular Weight 208.317
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C6D13NO4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MES-13d


MES-d13 is the deuterium labeled MES[1]. MES (2-Morpholinoethanesulphonic acid) is a buffering agent in biology and biochemistry. MES is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments[2][3].

 Names

Name 2-(n-morpholino)ethanesulfonic acid-d13
Synonym More Synonyms

 MES-13d Biological Activity

Description MES-d13 is the deuterium labeled MES[1]. MES (2-Morpholinoethanesulphonic acid) is a buffering agent in biology and biochemistry. MES is one of the Good's buffers, the buffer capacity ranging pH 5.5-7.0. MES is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. N E Good, et al. Hydrogen ion buffers for biological research. Biochemistry. 1966 Feb;5(2):467-77.  

[3]. Tomoko Kagenishi, et al. MES Buffer Affects Arabidopsis Root Apex Zonation and Root Growth by Suppressing Superoxide Generation in Root Apex. Front Plant Sci. 2016 Feb 187:79.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C6D13NO4S
Molecular Weight 208.317
Exact Mass 208.138123
PSA 75.22000
LogP -2.13
Index of Refraction 1.517

 Safety Information

Safety Phrases 22-24/25

 Synonyms

2-[(H)Morpholin-4-yl](H)ethane(H)sulfonic acid
2-[(H)-4-Morpholinyl](H)ethane(H)sulfonic acid
Morpholine-2,2,3,3,5,5,6,6-d-4-ethane-α,α,β,β-d-sulfonic acid-d