xylocytidine

Modify Date: 2026-07-01 17:49:27

xylocytidine Structure
xylocytidine structure
Common Name xylocytidine
CAS Number 3530-56-1 Molecular Weight 243.22
Density N/A Boiling Point N/A
Molecular Formula C9H13N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of xylocytidine


Xylocytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

 Names

Name 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonym More Synonyms

 xylocytidine Biological Activity

Description Xylocytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

 Chemical & Physical Properties

Molecular Formula C9H13N3O5
Molecular Weight 243.22
Exact Mass 243.08600
PSA 131.82000
InChIKey UHDGCWIWMRVCDJ-PXBUCIJWSA-N
SMILES Nc1ccn(C2OC(CO)C(O)C2O)c(=O)n1

 Precursor & DownStream

Precursor  0

DownStream  1

 xylocytidineBioassay

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Name: Toxicity of compound against mice was determined at a concentration of 2000 mg/kg
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL749907
Name: Toxicity of compound against mice was determined at a concentration of 100 mg/kg
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL747599
Name: Toxicity of compound against mice was determined at a concentration of 1200 mg/kg
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL747600
Name: Number of living cells on the proliferation of mouse myeloma cells SP2 was measured a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL803292
Name: Toxicity of compound against mice was determined at a concentration of 750 mg/kg
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL749910
Name: Number of living cells on the proliferation of mouse myeloma cells SP2 was measured a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL803291
Name: Toxicity of compound against mice was determined at a concentration of 250 mg/kg
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL749909
Name: Number of living cells on the proliferation of mouse myeloma cells SP2 was measured a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL803293
Name: Number of living cells on the proliferation of mouse myeloma cells SP2 was measured a...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL742243
Name: Efficacy expressed as number of surviving mice infected with herpetic encephalitis at...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL736927
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 Synonyms

Xylocytidine
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