CHLOTAZOLE

Modify Date: 2024-01-14 12:08:18

CHLOTAZOLE Structure
CHLOTAZOLE structure
Common Name CHLOTAZOLE
CAS Number 35317-79-4 Molecular Weight 247.53000
Density 1.765g/cm3 Boiling Point 301ºC at 760 mmHg
Molecular Formula C5H5Cl3N2OS Melting Point N/A
MSDS N/A Flash Point 135.8ºC

 Names

Name 2,2,2-trichloro-1-(1,3-thiazol-2-ylamino)ethanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.765g/cm3
Boiling Point 301ºC at 760 mmHg
Molecular Formula C5H5Cl3N2OS
Molecular Weight 247.53000
Flash Point 135.8ºC
Exact Mass 245.91900
PSA 73.39000
LogP 2.31660
Index of Refraction 1.68

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KM4950000
CHEMICAL NAME :
Ethanol, 2,2,2-trichloro-1-(2-thiazolylamino)-
CAS REGISTRY NUMBER :
35317-79-4
BEILSTEIN REFERENCE NO. :
0152089
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C5-H5-Cl3-N2-O-S
MOLECULAR WEIGHT :
247.53
WISWESSER LINE NOTATION :
T5N CSJ BMYQXGGG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 17,519,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 46,213,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
708 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2400361
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 17,519,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 17,519,1983

 Synthetic Route

~%

CHLOTAZOLE Structure

CHLOTAZOLE

CAS#:35317-79-4

Literature: Nelson et al. Journal of the American Pharmaceutical Association (1912-1977), 1947 , vol. 36, p. 349,351

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

2,2,2-trichloro-1-thiazol-2-ylamino-ethanol
2,2,2-Trichlor-1-thiazol-2-ylamino-aethanol
Clotazol
Khlotazol
Chlotazole
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