THP-CH3-ethyl propionate

Modify Date: 2024-01-10 17:53:54

THP-CH3-ethyl propionate structure	Common Name	THP-CH3-ethyl propionate
	CAS Number	3539-40-0	Molecular Weight	202.24800
	Density	1.05g/cm3	Boiling Point	292.7ºC at 760mmHg
	Molecular Formula	C₁₀H₁₈O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	125.6ºC

Use of THP-CH3-ethyl propionate

THP-CH3-ethyl propionate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	ethyl 2-(oxan-2-yloxy)propanoate
Synonym	More Synonyms

Description	THP-CH3-ethyl propionate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.05g/cm3
Boiling Point	292.7ºC at 760mmHg
Molecular Formula	C₁₀H₁₈O₄
Molecular Weight	202.24800
Flash Point	125.6ºC
Exact Mass	202.12100
PSA	44.76000
LogP	1.48120
Index of Refraction	1.448

3,4-Dihydro-2H-pyran structure

3,4-Dihydro-2H-pyran

CAS#:110-87-2

Ethyl lactate structure

Ethyl lactate

CAS#:97-64-3

[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid structure

[7,7-dimethyl-2...

CAS#:76-26-6

~%

THP-CH3-ethyl propionate Structure

THP-CH3-ethyl p...

CAS#:3539-40-0

Literature: Daiichi Pharmaceutical Co., Ltd. Patent: US5136059 A1, 1992 ;

Precursor 3
CAS#:110-87-2 3,4-Dihydro-2H-pyran CAS#:97-64-3 Ethyl lactate CAS#:76-26-6 [7,7-dimethyl-2...
DownStream 1
CAS#:76946-21-9 (2S)-2-((TETRAH...

Tetrahydropyranylethyllactat

DC Chemicals Limited
China
Product Name: THP-CH3-ethyl propionate
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Propanoic acid,2-[(tetrahydro-2H-pyran-2-yl)oxy]-, ethyl ester
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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