1-Fluoro-3,5-bis(trifluoromethyl)benzene

Modify Date: 2026-08-14 10:35:26

1-Fluoro-3,5-bis(trifluoromethyl)benzene structure	Common Name	1-Fluoro-3,5-bis(trifluoromethyl)benzene
	CAS Number	35564-19-3	Molecular Weight	232.098
	Density	1.4±0.1 g/cm3	Boiling Point	99.8±35.0 °C at 760 mmHg
	Molecular Formula	C₈H₃F₇	Melting Point	N/A
	MSDS	N/A	Flash Point	17.8±17.7 °C

Summary: 3,5-Bis-(trifluoromethyl)fluorobenzene (Chinese name: 3,5-双三氟甲基氟苯, CAS number: 35564-19-3), molecular formula C8H3F7, molecular weight 232.098. For research-use only, not for medical or clinical usage.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	3,5-Bis-(trifluoromethyl)fluorobenzene
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.4±0.1 g/cm3
Boiling Point	99.8±35.0 °C at 760 mmHg
Molecular Formula	C₈H₃F₇
Molecular Weight	232.098
Flash Point	17.8±17.7 °C
Exact Mass	232.012299
LogP	3.38
Vapour Pressure	43.4±0.2 mmHg at 25°C
Index of Refraction	1.368
InChIKey	ZBVDOILFQLAMEJ-UHFFFAOYSA-N
SMILES	Fc1cc(C(F)(F)F)cc(C(F)(F)F)c1

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26-36/37/39
HS Code	2903999090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

3,5-di(trifluor...

CAS#:328-75-6

1-Fluoro-3,5-bi...

CAS#:35564-19-3

Learn More

Literature: Journal of the American Chemical Society, , vol. 127, # 7 p. 2050 - 2051

3,5-Di(trifluor...

CAS#:328-74-5

1-Fluoro-3,5-bi...

CAS#:35564-19-3

Learn More

Literature: Journal of the American Chemical Society, , vol. 116, # 10 p. 4382 - 4390

Benzene,1,3-bis...

CAS#:881-99-2

1-Fluoro-3,5-bi...

CAS#:35564-19-3

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Literature: Journal of the Chemical Society [Section] B: Physical Organic, , p. 646 - 648

3,5-Bis(trifluo...

CAS#:328-70-1

~73%

1-Fluoro-3,5-bi...

CAS#:35564-19-3

Learn More

Literature: Sun, Haoran; DiMagno, Stephen G. Journal of the American Chemical Society, 2005 , vol. 127, # 7 p. 2050 - 2051

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 4
CAS#:328-70-1 3,5-Bis(trifluo... CAS#:328-75-6 3,5-di(trifluor... CAS#:328-74-5 3,5-Di(trifluor... CAS#:881-99-2 Benzene,1,3-bis...
DownStream 0

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2903999090
Summary	2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Drug reactivity against cysteamine in pH 7.4 PBS buffer assessed as half life at 250 ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4628237

Name: Inhibition of JAK3 (unknown origin) incubated for 45 mins by LC-MS/MS analysis
Source: ChEMBL
Target: Tyrosine-protein kinase JAK3
External Id: CHEMBL5231776

Name: Inhibition of JAK3 (unknown origin) at 100 uM preincubated for 1 hr followed by subst...
Source: ChEMBL
Target: Tyrosine-protein kinase JAK3
External Id: CHEMBL5231773

Name: Inhibition of MAP2K4 (unknown origin) at 100 uM preincubated for 1 hr followed by sub...
Source: ChEMBL
Target: Dual specificity mitogen-activated protein kinase kinase 4
External Id: CHEMBL5231772

Name: Inhibition of MELK (unknown origin) at 100 uM preincubated for 1 hr followed by subst...
Source: ChEMBL
Target: Maternal embryonic leucine zipper kinase
External Id: CHEMBL5231774

Name: Inhibition of BTK (unknown origin) at 100 uM preincubated for 1 hr followed by substr...
Source: ChEMBL
Target: Tyrosine-protein kinase BTK
External Id: CHEMBL5231769

Name: Aqueous stability of the compound assessed as compound degradation by measuring half ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5231768

Name: Inhibition of RSK2 (unknown origin) at 100 uM preincubated for 1 hr followed by subst...
Source: ChEMBL
Target: Ribosomal protein S6 kinase alpha-3
External Id: CHEMBL5231771

Name: Inhibition of ERK2 (unknown origin) at 100 uM preincubated for 1 hr followed by subst...
Source: ChEMBL
Target: Mitogen-activated protein kinase 1
External Id: CHEMBL5231770

Name: Thiol reactivity of compound assessed as kinetic rate constant by LC-MS analysis
Source: ChEMBL
Target: N/A
External Id: CHEMBL5231765

Total 19, Current Page 1 of 2

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

1-Fluoro-3,5-bis(trifluoromethyl)benzene

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the safety information for 3,5-Bis-(trifluoromethyl)fluorobenzene?

A: Safety information for 3,5-Bis-(trifluoromethyl)fluorobenzene: 26-36/37/39.

Q: What is the SMILES notation of 3,5-Bis-(trifluoromethyl)fluorobenzene?

A: SMILES notation of 3,5-Bis-(trifluoromethyl)fluorobenzene is Fc1cc(C(F)(F)F)cc(C(F)(F)F)c1.

Q: What is the boiling point of 3,5-Bis-(trifluoromethyl)fluorobenzene?

A: Boiling point of 3,5-Bis-(trifluoromethyl)fluorobenzene is 99.8±35.0 °C at 760 mmHg.

Q: What is the CAS number of 3,5-Bis-(trifluoromethyl)fluorobenzene?

A: CAS number of 3,5-Bis-(trifluoromethyl)fluorobenzene is 35564-19-3.

Q: What English synonyms does 3,5-Bis-(trifluoromethyl)fluorobenzene have?

A: English synonyms of 3,5-Bis-(trifluoromethyl)fluorobenzene: 1-Fluoro-3,5-bis(trifluoromethyl)benzene.

Q: What are the upstream materials of 3,5-Bis-(trifluoromethyl)fluorobenzene?

A: Related upstream materials(CAS) of 3,5-Bis-(trifluoromethyl)fluorobenzene: 328-70-1;328-75-6;328-74-5;881-99-2.

Q: What is the InChIKey of 3,5-Bis-(trifluoromethyl)fluorobenzene?

A: InChIKey of 3,5-Bis-(trifluoromethyl)fluorobenzene is ZBVDOILFQLAMEJ-UHFFFAOYSA-N.

Q: What is the molecular formula of 3,5-Bis-(trifluoromethyl)fluorobenzene?

A: Molecular formula of 3,5-Bis-(trifluoromethyl)fluorobenzene is C8H3F7.

Q: What is the English name of 3,5-Bis-(trifluoromethyl)fluorobenzene?

A: The English name of 3,5-Bis-(trifluoromethyl)fluorobenzene is 3,5-Bis-(trifluoromethyl)fluorobenzene.

Q: What is the molecular weight of 3,5-Bis-(trifluoromethyl)fluorobenzene?

A: Molecular weight of 3,5-Bis-(trifluoromethyl)fluorobenzene is 232.098.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1-Fluoro-3,5-bis(trifluoromethyl)benzene
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3,5-bis-(Trifluoromethyl)fluorobenzene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.