BVFP

Modify Date: 2025-08-21 07:08:11

BVFP structure	Common Name	BVFP
	CAS Number	357158-20-4	Molecular Weight	345.11
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₈BrF₃N₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BVFP

BVFP binds to the PGRN588–593 peptide with a Kd of 20 μM. BVFP can disrupt PGRN-SORT1 binding. BVFP also inhibits SORT1-mediated rPGRN endocytosis[1].

Name	BVFP

Description	BVFP binds to the PGRN588–593 peptide with a Kd of 20 μM. BVFP can disrupt PGRN-SORT1 binding. BVFP also inhibits SORT1-mediated rPGRN endocytosis[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Neurotensin Receptor Research Areas >> Neurological Disease
References	[1]. Lee WC, et al. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. Hum Mol Genet. 2014 Mar 15;23(6):1467-78.

Molecular Formula	C₁₃H₈BrF₃N₂O
Molecular Weight	345.11

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