BVFP

Modify Date: 2025-08-21 07:08:11

BVFP Structure
BVFP structure
 Common Name BVFP
CAS Number 357158-20-4 Molecular Weight 345.11
Density N/A Boiling Point N/A
Molecular Formula C13H8BrF3N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BVFP


BVFP binds to the PGRN588–593 peptide with a Kd of 20 μM. BVFP can disrupt PGRN-SORT1 binding. BVFP also inhibits SORT1-mediated rPGRN endocytosis[1].

 Names

Name BVFP

 BVFP Biological Activity

Description BVFP binds to the PGRN588–593 peptide with a Kd of 20 μM. BVFP can disrupt PGRN-SORT1 binding. BVFP also inhibits SORT1-mediated rPGRN endocytosis[1].
Related Catalog
References

[1]. Lee WC, et al. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. Hum Mol Genet. 2014 Mar 15;23(6):1467-78.  

 Chemical & Physical Properties

Molecular Formula C13H8BrF3N2O
Molecular Weight 345.11
InChIKey DMNBJHFWSKYYJK-SNAWJCMRSA-N
SMILES O=c1nc(C=Cc2cccc(Br)c2)cc(C(F)(F)F)[nH]1
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Chemsrc provides BVFP(CAS#:357158-20-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of BVFP are included as well.>> amp version: BVFP

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