4-(5-nitro-1H-benzo[d]imidazol-2-yl)thiazole
![4-(5-nitro-1H-benzo[d]imidazol-2-yl)thiazole Structure](https://image.chemsrc.com/caspic/338/3575-05-1.png)
4-(5-nitro-1H-benzo[d]imidazol-2-yl)thiazole structure
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Common Name | 4-(5-nitro-1H-benzo[d]imidazol-2-yl)thiazole | ||
|---|---|---|---|---|
| CAS Number | 3575-05-1 | Molecular Weight | 246.24500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H6N4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C10H6N4O2S |
|---|---|
| Molecular Weight | 246.24500 |
| Exact Mass | 246.02100 |
| PSA | 115.63000 |
| LogP | 3.11780 |
| InChIKey | LPEUFGNVMRMLRM-UHFFFAOYSA-N |
| SMILES | O=[N+]([O-])c1ccc2nc(-c3cscn3)[nH]c2c1 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2934999090 |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~56%
4-(5-nitro-1H-b... CAS#:3575-05-1 |
| Literature: Schiffmann, Rolf; Neugebauer, Alexander; Klein, Christian D. Journal of Medicinal Chemistry, 2006 , vol. 49, # 2 p. 511 - 522 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 1 | |
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| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of NLRP3 inflammasome activation in LPS-stimulated human THP1 cells assess...
Source: ChEMBL
Target: NACHT, LRR and PYD domains-containing protein 3
External Id: CHEMBL4324159
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Name: Inhibition of LPS/ATP induced IL-1beta release in human THP-1 cells at 10 uM pretreat...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5634866
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Name: Cytotoxicity against HUVEC assessed as inhibition of cell proliferation rate at 10 uM...
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL3587104
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Name: Inhibition of Mn2+ loaded MetAP expressed in Escherichia coli at upto 10 uM
Source: ChEMBL
Target: Methionine aminopeptidase
External Id: CHEMBL865845
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Name: Cytotoxicity against HUVEC assessed as inhibition of cell proliferation rate at 100 u...
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL3587105
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Name: Inhibition of Co2+ loaded MetAP expressed in Escherichia coli
Source: ChEMBL
Target: Methionine aminopeptidase
External Id: CHEMBL865844
|
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 5-Nitrothiabendazol |
| 2-/21,41-Thiazolyl/-5-nitrobenzimidazol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole? |
| A: Polar surface area (PSA) of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole is 115.63000. |
| Q: What is the molecular weight of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole? |
| A: Molecular weight of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole is 246.24500. |
| Q: What is the LogP of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole? |
| A: LogP of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole is 3.11780. |
| Q: What English synonyms does 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole have? |
| A: English synonyms of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole: 5-Nitrothiabendazol, 2-/21,41-Thiazolyl/-5-nitrobenzimidazol. |
| Q: What is the CAS number of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole? |
| A: CAS number of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole is 3575-05-1. |
| Q: What are the upstream materials of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole? |
| A: Related upstream materials(CAS) of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole: 148-79-8. |
| Q: What is the molecular formula of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole? |
| A: Molecular formula of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole is C10H6N4O2S. |
| Q: What is the SMILES notation of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole? |
| A: SMILES notation of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole is O=[N+]([O-])c1ccc2nc(-c3cscn3)[nH]c2c1. |
| Q: What is the InChIKey of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole? |
| A: InChIKey of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole is LPEUFGNVMRMLRM-UHFFFAOYSA-N. |
| Q: What is the English name of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole? |
| A: The English name of 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole is 4-(6-nitro-1H-benzimidazol-2-yl)-1,3-thiazole. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Dayang Chem (Hangzhou) Co., Ltd. |