5-Chloropyrazine-2-carboxylic acid

Modify Date: 2026-07-13 07:42:54

5-Chloropyrazine-2-carboxylic acid Structure
5-Chloropyrazine-2-carboxylic acid structure
Common Name 5-Chloropyrazine-2-carboxylic acid
CAS Number 36070-80-1 Molecular Weight 158.542
Density 1.6±0.1 g/cm3 Boiling Point 330.9±37.0 °C at 760 mmHg
Molecular Formula C5H3ClN2O2 Melting Point 150-151℃
MSDS N/A Flash Point 153.9±26.5 °C

Summary: 5-Chloropyrazine-2-carboxylic acid (Chinese name: 5-氯吡嗪-2-羧酸,CAS number: 36070-80-1) is a white solid powder with molecular formula C5H3ClN2O2 and molecular weight 158.542. The compound is a white solid powder, with a melting point of 150-151°C, boiling point of 330.9±37.0 °C at 760 mmHg, and density of 1.6±0.1 g/cm3. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 5-Chloropyrazine-2-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.6±0.1 g/cm3
Boiling Point 330.9±37.0 °C at 760 mmHg
Melting Point 150-151℃
Molecular Formula C5H3ClN2O2
Molecular Weight 158.542
Flash Point 153.9±26.5 °C
Exact Mass 157.988312
PSA 63.08000
LogP -0.28
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.598
InChIKey FXJOTWLLDJYKAG-UHFFFAOYSA-N
SMILES O=C(O)c1cnc(Cl)cn1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
5-Chloropyrazine-2-carboxylic acid
Product Name:
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H315:Causes skin irritation
H319:Causes serious eye irritation
H335:May cause respiratory irritation
P261:Avoid breathing dust/fume/gas/mist/vapours/spray
Wear protective gloves/protective clothing/eye protection/face protection
P280:
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing
P304+P340:IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
P405:Store locked up

Section3. Composition/information on ingredients.
5-Chloropyrazine-2-carboxylic acid
Ingredient name:
CAS number:36070-80-1

Section4. First aid measures
Immediately wash skin with copious amounts of water for at least 15 minutes while removing
Skin contact:
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.
Ingestion:

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Not specified
Appearance:
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula:C5H3ClN2O2
Molecular weight:158.5

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi
HS Code 2933990090

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 5-Chloropyrazine-2-carboxylic acidBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Minimum Inhibitory Concentration against Mycobacterium tuberculosis ATCC 27294
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL750947
Name: Drug level in serum-free RPMI-1640 medium treated with [4-bromo-2-[[4-(trifluoromethy...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3615895
Name: Minimum Inhibitory Concentration against clinical isolates of Mycobacterium kansasii ...
Source: ChEMBL
Target: Mycobacterium kansasii
External Id: CHEMBL751696
Name: Retention time of the compound in serum-free RPMI-1640 medium containing 10% DMSO at ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3615892
Name: Minimum Inhibitory Concentration in clinical isolates against Mycobacterium avium com...
Source: ChEMBL
Target: Mycobacterium avium
External Id: CHEMBL747039
Name: Minimum Inhibitory Concentration against Mycobacterium tuberculosis ATCC 35801
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL750949
Name: Minimum Inhibitory Concentration in clinical isolates against Mycobacterium avium com...
Source: ChEMBL
Target: Mycobacterium avium
External Id: CHEMBL747038
Name: Minimum Inhibitory Concentration against Mycobacterium tuberculosis ATCC 35828 PZA re...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL750950
Name: Antimycobacterial activity against Mycobacterium bovis BCG Pasteur ATCC35734 assessed...
Source: ChEMBL
Target: Mycobacterium tuberculosis variant bovis
External Id: CHEMBL5099097
Name: Antimycobacterial activity against Mycobacterium abscessus ATCC 19977 after 7 days by...
Source: ChEMBL
Target: Mycobacteroides abscessus
External Id: CHEMBL3615874
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

MFCD09033269
5-Chloro-pyrazine-2-carboxylic acid
Pyrazinecarboxylic acid,5-chloro
5-Chloropyrazine-2-carboxylic acid
5-Chloro-2-pyrazinecarboxylic acid
2-Carboxy-5-chloropyrazine
5-Chlopopyrazine-2-carboxylic acid
5-Chlorpyrazin-2-carbonsaeure
5-Chloropyrazinoic acid
5-Chloro-2-Pyrazine Carboxylic Acid
5-Chloropyrazinecarboxylic Acid
5-Chloro-2-pyrazine carboxylicacid(MFCD00190599)

 5-Chloropyrazine-2-carboxylic acid | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What English synonyms does 5-Chloropyrazine-2-carboxylic acid have?
A: English synonyms of 5-Chloropyrazine-2-carboxylic acid: MFCD09033269, 5-Chloro-pyrazine-2-carboxylic acid, Pyrazinecarboxylic acid,5-chloro, 5-Chloropyrazine-2-carboxylic acid, 5-Chloro-2-pyrazinecarboxylic acid, 2-Carboxy-5-chloropyrazine, 5-Chlopopyrazine-2-carboxylic acid, 5-Chlorpyrazin-2-carbonsaeure, 5-Chloropyrazinoic acid, 5-Chloro-2-Pyrazine Carboxylic Acid, 5-Chloropyrazinecarboxylic Acid, 5-Chloro-2-pyrazine carboxylicacid(MFCD00190599).
Q: What is the polar surface area (PSA) of 5-Chloropyrazine-2-carboxylic acid?
A: Polar surface area (PSA) of 5-Chloropyrazine-2-carboxylic acid is 63.08000.
Q: What is the boiling point of 5-Chloropyrazine-2-carboxylic acid?
A: Boiling point of 5-Chloropyrazine-2-carboxylic acid is 330.9±37.0 °C at 760 mmHg.
Q: What is the InChIKey of 5-Chloropyrazine-2-carboxylic acid?
A: InChIKey of 5-Chloropyrazine-2-carboxylic acid is FXJOTWLLDJYKAG-UHFFFAOYSA-N.
Q: What is the English name of 5-Chloropyrazine-2-carboxylic acid?
A: The English name of 5-Chloropyrazine-2-carboxylic acid is 5-Chloropyrazine-2-carboxylic acid.
Q: What is the melting point of 5-Chloropyrazine-2-carboxylic acid?
A: Melting point of 5-Chloropyrazine-2-carboxylic acid is 150-151℃.
Q: What is the molecular weight of 5-Chloropyrazine-2-carboxylic acid?
A: Molecular weight of 5-Chloropyrazine-2-carboxylic acid is 158.542.
Q: What is the CAS number of 5-Chloropyrazine-2-carboxylic acid?
A: CAS number of 5-Chloropyrazine-2-carboxylic acid is 36070-80-1.
Q: What is the SMILES notation of 5-Chloropyrazine-2-carboxylic acid?
A: SMILES notation of 5-Chloropyrazine-2-carboxylic acid is O=C(O)c1cnc(Cl)cn1.
Q: What is the molecular formula of 5-Chloropyrazine-2-carboxylic acid?
A: Molecular formula of 5-Chloropyrazine-2-carboxylic acid is C5H3ClN2O2.

 5-Chloropyrazine-2-carboxylic acidfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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