F16
Modify Date: 2024-01-06 13:47:20
F16 structure
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Common Name | F16 | ||
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| CAS Number | 36098-33-6 | Molecular Weight | 362.208 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H15IN2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of F16F16 is a small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines. 1, F16 induced cell cycle arrest in sensitive mouse tumor and human cancer cell lines.2, Prolonged incubation with 3 uM F16 resulted in increased cell death of F16-sensitive cells but not of F16-resistant ones.3, F16 caused apoptosis in A6 cells.4, F16 caused a dramatic decrease in the number of cells in S phase and an increase in the percentage of cells in G1 phase.5, F16 is capable of inhibiting oxidative phosphorylation and inducing mitochondrial transmembrane depolarization. |
| Name | 3-[2-(1-methylpyridin-1-ium-4-yl)ethenyl]-1H-indole,iodide |
|---|---|
| Synonym | More Synonyms |
| Description | F16 is a small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines. 1, F16 induced cell cycle arrest in sensitive mouse tumor and human cancer cell lines.2, Prolonged incubation with 3 uM F16 resulted in increased cell death of F16-sensitive cells but not of F16-resistant ones.3, F16 caused apoptosis in A6 cells.4, F16 caused a dramatic decrease in the number of cells in S phase and an increase in the percentage of cells in G1 phase.5, F16 is capable of inhibiting oxidative phosphorylation and inducing mitochondrial transmembrane depolarization. |
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| Related Catalog | |
| References |
| Molecular Formula | C16H15IN2 |
|---|---|
| Molecular Weight | 362.208 |
| Exact Mass | 362.027985 |
| PSA | 19.67000 |
| LogP | 0.16680 |
| Storage condition | 2-8℃ |
| 4-[(e)-2-(1h-indol-3-yl)-vinyl]-1-methyl-pyridinium |
| in1341 |
| Pyridinium, 4-[(E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-, iodide (1:1) |
| Pyridinium, 4-(2-indol-3-ylvinyl)-1-methyl-, iodide |
| 4-[(E)-2-(1H-Indol-3-yl)vinyl]-1-methylpyridinium iodide |
| F16 |