OT-R antagonist 2

Modify Date: 2024-01-11 11:42:03

OT-R antagonist 2 structure	Common Name	OT-R antagonist 2
	CAS Number	364071-16-9	Molecular Weight	471.548
	Density	1.2±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₉N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of OT-R antagonist 2

OT-R antagonist 2 is a nonpeptide low molecular weight OT-R antagonist. OT-R antagonist 2 inhibitis IP3-Synthesis, rat OT-R (IC50 = 0.33 μM).IC50 value: 0.33μMTarget: oxytocin receptor

Name	OT-R antagonist 2
Synonym	More Synonyms

Description	OT-R antagonist 2 is a nonpeptide low molecular weight OT-R antagonist. OT-R antagonist 2 inhibitis IP3-Synthesis, rat OT-R (IC50 = 0.33 μM).IC50 value: 0.33μMTarget: oxytocin receptor
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Oxytocin Receptor Research Areas >> Others
References	[1]. Cirillo R, et al. Pharmacology of (2S,4Z)-N-[(2S)-2-hydroxy-2-phenylethyl]-4-(methoxyimino) -1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide, a new potent and selective nonpeptide antagonist of the oxytocin receptor. J Pharmacol Exp T [2]. William Nadler, et al. Method for preparing pyrrolidine oximes. WO/2005082848/A2. [3]. Serge Halazy, et al. Pharmaceutically active pyrrolidine derivatives as bax inhibitors.WO/2001074769/A1. [4]. Serge Halazy, et al. Pharmaceutically active pyrrolidine derivatives as bax inhibitors. WO/2001072705/A1.

Description

OT-R antagonist 2 is a nonpeptide low molecular weight OT-R antagonist. OT-R antagonist 2 inhibitis IP3-Synthesis, rat OT-R (IC50 = 0.33 μM).IC50 value: 0.33μMTarget: oxytocin receptor

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Oxytocin Receptor

Research Areas >> Others

References

[1]. Cirillo R, et al. Pharmacology of (2S,4Z)-N-[(2S)-2-hydroxy-2-phenylethyl]-4-(methoxyimino) -1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide, a new potent and selective nonpeptide antagonist of the oxytocin receptor. J Pharmacol Exp T

[2]. William Nadler, et al. Method for preparing pyrrolidine oximes. WO/2005082848/A2.

[3]. Serge Halazy, et al. Pharmaceutically active pyrrolidine derivatives as bax inhibitors.WO/2001074769/A1.

[4]. Serge Halazy, et al. Pharmaceutically active pyrrolidine derivatives as bax inhibitors. WO/2001072705/A1.

Density	1.2±0.1 g/cm3
Molecular Formula	C₂₈H₂₉N₃O₄
Molecular Weight	471.548
Exact Mass	471.215820
LogP	2.80
Index of Refraction	1.618
Storage condition	2-8℃

(4E)-N-[(2S)-2-Hydroxy-2-phenylethyl]-4-(methoxyimino)-1-[(2'-methyl-4-biphenylyl)carbonyl]-L-prolinamide

2-Pyrrolidinecarboxamide, N-[(2S)-2-hydroxy-2-phenylethyl]-4-(methoxyimino)-1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-, (2S,4E)-

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OT-R antagonist 2

Use of OT-R antagonist 2

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OT-R antagonist 2 Biological Activity

Chemical & Physical Properties

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