Isopropyl-beta-D-thiogalactopyranoside
Isopropyl-beta-D-thiogalactopyranoside structure
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Common Name | Isopropyl-beta-D-thiogalactopyranoside | ||
|---|---|---|---|---|
| CAS Number | 367-93-1 | Molecular Weight | 238.301 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 438.4±45.0 °C at 760 mmHg | |
| Molecular Formula | C9H18O5S | Melting Point | 105 °C | |
| MSDS | USA | Flash Point | 218.9±28.7 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
Use of Isopropyl-beta-D-thiogalactopyranosideIPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | isopropyl β-D-thiogalactopyranoside |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. |
|---|---|
| Related Catalog | |
| In Vitro | IPTG uptake by E. coli can be independent of the action of lactose permease, since other transport pathways are also involved. At low concentration, IPTG enters cells through lactose permease, but at high concentrations (typically used for protein induction), IPTG can enter the cells independently of lactose permease[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 438.4±45.0 °C at 760 mmHg |
| Melting Point | 105 °C |
| Molecular Formula | C9H18O5S |
| Molecular Weight | 238.301 |
| Flash Point | 218.9±28.7 °C |
| Exact Mass | 238.087494 |
| PSA | 115.45000 |
| LogP | -1.01 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.578 |
| InChIKey | BPHPUYQFMNQIOC-NXRLNHOXSA-N |
| SMILES | CC(C)SC1OC(CO)C(O)C(O)C1O |
| Water Solubility | soluble |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319-H351 |
| Precautionary Statements | P281-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R19;R40;R66 |
| Safety Phrases | S23-S24/25-S36/37-S22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2932999099 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Isopropyl-beta-... CAS#:367-93-1 |
| Literature: Schmidt, Richard R.; Stumpp, Michael Liebigs Annalen der Chemie, 1983 , # 7 p. 1249 - 1256 |
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| Literature: Li, Aixiao; Kong, Fanzuo Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 3 p. 839 - 853 |
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| Literature: Thiem, Joachim; Wiesner, Matthias Carbohydrate Research, 1993 , vol. 249, # 1 p. 197 - 206 |
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| Literature: Schmidt, Richard R.; Stumpp, Michael Liebigs Annalen der Chemie, 1983 , # 7 p. 1249 - 1256 |
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| Literature: Helferich; Tuerk Chemische Berichte, 1956 , vol. 89, p. 2215,2218 |
![[(3S,4S,6S)-3,4,5-triacetyloxy-6-propan-2-ylsulfanyloxan-2-yl]methyl acetate structure](https://image.chemsrc.com/caspic/028/55692-87-0.png)
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
|---|---|
| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is required for production of progeny viruses.
J. Virol. 89(9) , 4918-31, (2015) The ORF45 protein of Kaposi's sarcoma-associated herpesvirus (KSHV) is a gammaherpesvirus-specific immediate-early tegument protein. Our previous studies have revealed its crucial roles in both early ... |
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Phospho-tyrosine dependent protein-protein interaction network.
Mol. Syst. Biol. 11(3) , 794, (2015) Post-translational protein modifications, such as tyrosine phosphorylation, regulate protein-protein interactions (PPIs) critical for signal processing and cellular phenotypes. We extended an establis... |
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An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence.
Proc. Natl. Acad. Sci. U. S. A. 112(7) , E747-56, (2015) The nucleotide cyclic di-3',5'- adenosine monophosphate (c-di-AMP) was recently identified as an essential and widespread second messenger in bacterial signaling. Among c-di-AMP-producing bacteria, al... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| MFCD00063273 |
| isopropyl beta-D-thiogalactopyranoside |
| Isopropyl-b-D-thiogalactopyranoside |
| UNII-X73VV2246B |
| (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-propan-2-ylsulfanyloxane-3,4,5-triol |
| Isopropyl β-D-1-thiogalactopyranoside |
| propan-2-yl 1-thio-β-D-galactopyranoside |
| Isopropyl 1-thio-b-D-galactopyranoside |
| Isopropyl-β-D-thiogalactoside |
| Isopropyl β-D-thiogalactoside |
| 1-Methylethyl 1-thio-β-D-galactopyranoside |
| Isopropyl β-D-thiogalactopyranoside |
| Isopropyl-beta-D-thiogalactopyranoside |
| Isopropyl 1-thio-β-D-galactopyranoside |
| Isopropyl-β-D-thiogalactopyranoside |
| EINECS 206-703-0 |
| Isopropyl β-D-thiogalactoside (IPTG) |
| IPTG |
| 1-(Isopropylthio)-β-Galactopyranside |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of isopropyl β-D-thiogalactopyranoside? |
| A: InChIKey of isopropyl β-D-thiogalactopyranoside is BPHPUYQFMNQIOC-NXRLNHOXSA-N. |
| Q: What is the safety information for isopropyl β-D-thiogalactopyranoside? |
| A: Safety information for isopropyl β-D-thiogalactopyranoside: S23-S24/25-S36/37-S22. |
| Q: What is the English name of isopropyl β-D-thiogalactopyranoside? |
| A: The English name of isopropyl β-D-thiogalactopyranoside is isopropyl β-D-thiogalactopyranoside. |
| Q: What is the SMILES notation of isopropyl β-D-thiogalactopyranoside? |
| A: SMILES notation of isopropyl β-D-thiogalactopyranoside is CC(C)SC1OC(CO)C(O)C(O)C1O. |
| Q: What is the molecular formula of isopropyl β-D-thiogalactopyranoside? |
| A: Molecular formula of isopropyl β-D-thiogalactopyranoside is C9H18O5S. |
| Q: What are the uses of isopropyl β-D-thiogalactopyranoside? |
| A: Main uses of isopropyl β-D-thiogalactopyranoside: IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. |
| Q: How is the water solubility of isopropyl β-D-thiogalactopyranoside? |
| A: Water solubility of isopropyl β-D-thiogalactopyranoside: soluble. |
| Q: What is the CAS number of isopropyl β-D-thiogalactopyranoside? |
| A: CAS number of isopropyl β-D-thiogalactopyranoside is 367-93-1. |
| Q: What is the LogP of isopropyl β-D-thiogalactopyranoside? |
| A: LogP of isopropyl β-D-thiogalactopyranoside is -1.01. |
| Q: What is the molecular weight of isopropyl β-D-thiogalactopyranoside? |
| A: Molecular weight of isopropyl β-D-thiogalactopyranoside is 238.301. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| naturewill |
| Henan Tianfu Chemical Co., Ltd. |