Pholedrine
Pholedrine structure
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Common Name | Pholedrine | ||
|---|---|---|---|---|
| CAS Number | 370-14-9 | Molecular Weight | 165.23200 | |
| Density | 1.014g/cm3 | Boiling Point | 279.4ºC at 760mmHg | |
| Molecular Formula | C10H15NO | Melting Point | 162-163° | |
| MSDS | Chinese USA | Flash Point | 109ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of PholedrinePholedrine is an Autonomic Agent. It is a a sympathomimetic vasoconstrictive drug. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | rac Pholedrine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.014g/cm3 |
|---|---|
| Boiling Point | 279.4ºC at 760mmHg |
| Melting Point | 162-163° |
| Molecular Formula | C10H15NO |
| Molecular Weight | 165.23200 |
| Flash Point | 109ºC |
| Exact Mass | 165.11500 |
| PSA | 32.26000 |
| LogP | 1.93350 |
| Index of Refraction | 1.532 |
| InChIKey | SBUQZKJEOOQSBV-UHFFFAOYSA-N |
| SMILES | CNC(C)Cc1ccc(O)cc1 |
| Storage condition | −20°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36-45-36/37-16-7 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | SL8400000 |
| HS Code | 2922299090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Pholedrine CAS#:370-14-9 |
| Literature: Knoll A.G. Patent: DE674753 , 1936 ; DRP/DRBP Org.Chem. |
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Pholedrine CAS#:370-14-9 |
| Literature: Knoll A.G. Patent: DE672372 , 1936 ; DRP/DRBP Org.Chem. |
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Pholedrine CAS#:370-14-9 |
| Literature: Knoll A.G. Patent: DE672372 , 1936 ; DRP/DRBP Org.Chem. |
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Pholedrine CAS#:370-14-9
Learn More
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| Literature: Blume Arzneimittel-Forschung/Drug Research, 1981 , vol. 31, # 5 p. 805 - 809 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 4 | |
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| DownStream 1 | |
CAS#:114860-09-2This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2922299090 |
|---|---|
| Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Identification of new urinary metabolites of famprofazone in humans.
J. Anal. Toxicol. 22(1) , 55-60, (1998) Urinary metabolites of famprofazone following oral administration in humans were identified by gas chromatography-mass spectrometry with electron impact-ionization and comparison with the spectra and ... |
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Urinary excretion of the main metabolites of methamphetamine, including p-hydroxymethamphetamine-sulfate and p-hydroxymethamphetamine-glucuronide, in humans and rats.
Xenobiotica 36(2-3) , 259-67, (2006) The urinary concentrations of the main metabolites of methamphetamine (MA), specifically p-hydroxymethamphetamine-sulfate (p-OHMA-Sul) and p-hydroxymethamphetamine-glucuronide (p-OHMA-Glu), were direc... |
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LC-MS/MS analysis of pholedrine in a fatal intoxication case.
Forensic Sci. Int. 133(1-2) , 101-6, (2003) Pholedrine (4'-hydroxymethamphetamine) is a cardiovascular agent exerting hypertensive and adrenergic effects. High doses may cause a drop in the peripheral circulation blood flow and increase blood p... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: ULK1_INH_LUMI_1536_1X%INH PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-[2-(methylamino)propyl]phenol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the downstream products of rac Pholedrine? |
| A: Related downstream products(CAS) of rac Pholedrine: 114860-09-2. |
| Q: What is the melting point of rac Pholedrine? |
| A: Melting point of rac Pholedrine is 162-163°. |
| Q: What are the upstream materials of rac Pholedrine? |
| A: Related upstream materials(CAS) of rac Pholedrine: 770-39-8;74-89-5;103-86-6;50-00-0. |
| Q: What is the molecular formula of rac Pholedrine? |
| A: Molecular formula of rac Pholedrine is C10H15NO. |
| Q: What is the SMILES notation of rac Pholedrine? |
| A: SMILES notation of rac Pholedrine is CNC(C)Cc1ccc(O)cc1. |
| Q: What are the uses of rac Pholedrine? |
| A: Main uses of rac Pholedrine: Pholedrine is an Autonomic Agent. It is a a sympathomimetic vasoconstrictive drug. |
| Q: What is the InChIKey of rac Pholedrine? |
| A: InChIKey of rac Pholedrine is SBUQZKJEOOQSBV-UHFFFAOYSA-N. |
| Q: What English synonyms does rac Pholedrine have? |
| A: English synonyms of rac Pholedrine: 4-[2-(methylamino)propyl]phenol. |
| Q: What are the storage conditions for rac Pholedrine? |
| A: Storage conditions for rac Pholedrine: −20°C. |
| Q: What is the LogP of rac Pholedrine? |
| A: LogP of rac Pholedrine is 1.93350. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |