Mibolerone

Modify Date: 2024-01-07 12:11:40

Mibolerone structure	Common Name	Mibolerone
	CAS Number	3704-09-4	Molecular Weight	302.45100
	Density	1.1g/cm3	Boiling Point	440.5ºC at 760mmHg
	Molecular Formula	C₂₀H₃₀O₂	Melting Point	168-171ºC
	MSDS	Chinese USA	Flash Point	187.8ºC
	Symbol	GHS08	Signal Word	Danger

Name	mibolerone
Synonym	More Synonyms

Density	1.1g/cm3
Boiling Point	440.5ºC at 760mmHg
Melting Point	168-171ºC
Molecular Formula	C₂₀H₃₀O₂
Molecular Weight	302.45100
Flash Point	187.8ºC
Exact Mass	302.22500
PSA	37.30000
LogP	4.12520
Index of Refraction	1.553
Storage condition	Controlled Substance, -20?C Freezer

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KG7980000

CHEMICAL NAME :: Estr-4-en-3-one, 17-beta-hydroxy-7-alpha,17-dimethyl-

CAS REGISTRY NUMBER :: 3704-09-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C20-H30-O2

MOLECULAR WEIGHT :: 302.50

WISWESSER LINE NOTATION :: L E5 B666 OVTJ E1 FQ F1 K1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 8985 ug/kg/9.6Y-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Reproductive - Tumorigenic effects - ovarian tumors

REFERENCE :: TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 13,177,1985 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 800 ug/kg

SEX/DURATION :: female 10 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: STEDAM Steroids. (Holden-Day Inc., 4432 Telegraph Ave., Oakland, CA 94609) V.1- 1963- Volume(issue)/page/year: 9,235,1967

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 196 ug/kg

SEX/DURATION :: female 6-61 day(s) after conception lactating female 42 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: AJVRAH American Journal of Veterinary Research. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.1- 1940- Volume(issue)/page/year: 39,837,1978

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H360
Precautionary Statements	P201-P308 + P313
Hazard Codes	T
Risk Phrases	60-63
Safety Phrases	36-45
RIDADR	NONH for all modes of transport

In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5alpha-reductase inhibitors.

J. Steroid Biochem. Mol. Biol. 111(3-5) , 275-81, (2008)

In this study, we report the synthesis and biological evaluation of several new 3-substituted pregna-4,16-diene-6,20-dione derivatives (11a-11d). These compounds were prepared from the commercially av...

Steroid and beta-adrenergic receptor modifications in target organs of broiler chickens fed with a diet containing beta2-adrenergic agents.

Food Chem. Toxicol. 46(6) , 2239-43, (2008)

The illegal use of beta2-agonists as repartitioning agents to improve production performance and carcass composition can induce changes in various organs of exposed animals. The aim of the present stu...

Steroids with a carbamate function at C-17, a novel class of inhibitors for human and hamster steroid 5alpha-reductase.

J. Steroid Biochem. Mol. Biol. 107(1-2) , 48-56, (2007)

In order to study the biological activity of the two novel steroidal carbamates derivatives: 8a and 8b, we determined the concentration of both compounds that inhibit the 50% of the activity of human ...

MIBOLERONE

U-10,997

Miboleron

CDB 904

Miboleronum

[3H]-Mibolerone

MFCD00221774

(7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-7,13,17-trimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

Cheque

Mibolerona

EINECS 223-046-5

Mibolerone

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Articles25

Synonyms