tibric acid

Modify Date: 2025-08-25 16:31:47

tibric acid Structure
tibric acid structure
Common Name tibric acid
CAS Number 37087-94-8 Molecular Weight 331.82
Density 1.331g/cm3 Boiling Point 488.2ºC at 760mmHg
Molecular Formula C14H18ClNO4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of tibric acid


Tibric acid (CP 18524) has similar effects to those of hypolipidemic agents. Tibric acid has orally active triglyceride-lowering effects. Tibric acid can be used for research of hypertriglyceridemia[1][2].

 Names

Name 2-chloro-5-[(3S,5R)-3,5-dimethylpiperidin-1-yl]sulfonylbenzoic acid
Synonym More Synonyms

 tibric acid Biological Activity

Description Tibric acid (CP 18524) has similar effects to those of hypolipidemic agents. Tibric acid has orally active triglyceride-lowering effects. Tibric acid can be used for research of hypertriglyceridemia[1][2].
Related Catalog
References

[1]. Bielmann P, et al. Dose-response to tibric acid: a new hypolipidemic drug in type IV hyperlipoproteinemia. Clin Pharmacol Ther. 1975 May;17(5):606-11.  

[2]. Cayen MN, et al. Effect of tibric acid on hepatic cholesterol synthesis in rats. Lipids. 1977 Aug;12(8):684-8.  

 Chemical & Physical Properties

Density 1.331g/cm3
Boiling Point 488.2ºC at 760mmHg
Molecular Formula C14H18ClNO4S
Molecular Weight 331.82
Exact Mass 331.06500
PSA 83.06000
LogP 3.72350
Index of Refraction 1.562
InChIKey IFXSWTIWFGIXQO-AOOOYVTPSA-N
SMILES CC1CC(C)CN(S(=O)(=O)c2ccc(Cl)c(C(=O)O)c2)C1

 Safety Information

HS Code 2935009090

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 tibric acidBioassay

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Name: Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum act...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3137722
Name: Highest frequency of moderate liver toxicity observed during clinical trials, express...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3137723
Name: Acute liver toxicity defined via clinical observations and clear clinical-chemistry r...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137724
Name: Carcinogenesis bioassays from the Carcinogenic Potency Database (CPDB)
Source: 25294
Target: N/A
External Id: cpdb
Name: Highest frequency of acute liver toxicity observed during clinical trials, expressed ...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3137725
Name: Cytolytic liver toxicity, either proven histopathologically or where the ratio of max...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137726
Name: Choleostatic liver toxicity, either proven histopathologically or where the ratio of ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137727
Name: Severe hepatitis, defined as possibly life-threatening liver failure or through clini...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137728
Name: Chronic liver disease either proven histopathologically, or through a chonic elevatio...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137729
Name: Cirrhosis, proven histopathologically. Value is number of references indexed. [column...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137730
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 Synonyms

EINECS 253-344-0
C14H18ClNO4S
Tibric acid
2-Chloro-5-(3,5-dimethylpiperidinosulphonyl)benzoic acid
Acido tibrico [INN-Spanish]
EINECS 246-198-4
Acide tibrique [INN-French]
Acidum tibricum [INN-Latin]
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