Hyaluronidase

Modify Date: 2024-01-04 19:23:59

Hyaluronidase Structure
Hyaluronidase structure
Common Name Hyaluronidase
CAS Number 37326-33-3 Molecular Weight 342.300
Density 1.5±0.1 g/cm3 Boiling Point 598.6±50.0 °C at 760 mmHg
Molecular Formula C18H14O7 Melting Point N/A
MSDS Chinese USA Flash Point 223.2±23.6 °C

 Use of Hyaluronidase


Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive[1][2].

 Names

Name Hyaluronidase
Synonym More Synonyms

 Hyaluronidase Biological Activity

Description Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive[1][2].
Related Catalog
References

[1]. Vartanian AJ, et al. Injected hyaluronidase reduces restylane-mediated cutaneous augmentation. Arch Facial Plast Surg. 2005 Jul-Aug;7(4):231-7.

[2]. Brandon E, et al. The Use of Hyaluronidase in Cosmetic Dermatology: A Review of the Literature. J Clin Investigat Dermatol. 2015;3(2): 7.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 598.6±50.0 °C at 760 mmHg
Molecular Formula C18H14O7
Molecular Weight 342.300
Flash Point 223.2±23.6 °C
Exact Mass 342.073944
LogP 2.41
Appearance of Characters powder | yellow-brown
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.642
Storage condition −20°C
Water Solubility Soluble in water, practically insoluble in acetone and in anhydrous ethanol

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles105

More Articles
Faster fertilization rate in conspecific versus heterospecific matings in house mice.

Evolution 63 , 20-8, (2010)

Barriers to gene flow can arise at any stage in the reproductive sequence. Most studies of reproductive isolation focus on premating or postzygotic phenotypes, leaving the importance of differences in...

Putting on the brakes: Bacterial impediment of wound healing.

Sci. Rep. 5 , 14003, (2015)

The epithelium provides a crucial barrier to infection, and its integrity requires efficient wound healing. Bacterial cells and secretomes from a subset of tested species of bacteria inhibited human a...

Focal experimental injury leads to widespread gene expression and histologic changes in equine flexor tendons.

PLoS ONE 10(4) , e0122220, (2015)

It is not known how extensively a localised flexor tendon injury affects the entire tendon. This study examined the extent of and relationship between histopathologic and gene expression changes in eq...

 Synonyms

2,4-Bis(1,3-benzodioxol-5-yl)-4-oxobutanoic acid
Neopermease
1,3-Benzodioxole-5-butanoic acid, α-1,3-benzodioxol-5-yl-γ-oxo-
Hydase
EINECS 253-464-3
Hyaluronoglucosidase
MFCD00131351
Hyaluronoglucosaminidase
Chondroitinase