Cephaeline dihydrochloride

Modify Date: 2025-08-21 20:00:08

Cephaeline dihydrochloride structure	Common Name	Cephaeline dihydrochloride
	CAS Number	3738-70-3	Molecular Weight	539.534
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₄₀Cl₂N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cephaeline dihydrochloride

Cephaeline hydrochloride ((-)-Cephaeline hydrochloride) is a phenolic alkaloid in Indian Ipecac roots. Cephaeline hydrochloride exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections[1][2].

Name	cephaeline hydrochloride
Synonym	More Synonyms

Description	Cephaeline hydrochloride ((-)-Cephaeline hydrochloride) is a phenolic alkaloid in Indian Ipecac roots. Cephaeline hydrochloride exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection Signaling Pathways >> Anti-infection >> Filovirus
References	[1]. N.P.Sahu, et al. Determination of emetine and cephaeline in Ipecac roots by high- performance liquid chromatography. Journal of Chromatography A. 1982 Apr; 238( 2):525-529. [2]. Yang S, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discov. 2018 Jun 5;4:31.

Description

Related Catalog

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Filovirus

References

[1]. N.P.Sahu, et al. Determination of emetine and cephaeline in Ipecac roots by high- performance liquid chromatography. Journal of Chromatography A. 1982 Apr; 238( 2):525-529.

[2]. Yang S, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discov. 2018 Jun 5;4:31.

Molecular Formula	C₂₈H₄₀Cl₂N₂O₄
Molecular Weight	539.534
Exact Mass	538.236511
PSA	63.19000
LogP	6.51110
Storage condition	2-8C

Name: Inhibition of HIV1 RT at 200 ug/ml
Source: ChEMBL
Target: Reverse transcriptase/RNaseH
External Id: CHEMBL1018095

Name: Inhibition of HIV1 RT
Source: ChEMBL
Target: Reverse transcriptase/RNaseH
External Id: CHEMBL1018093

Name: Antiviral activity against Ebolavirus infected in african green monkey COS1 cells ass...
Source: ChEMBL
Target: Ebolavirus
External Id: CHEMBL1639010

Name: Cytotoxicity against african green monkey COS1 cells assessed as reduction in cell vi...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1639011

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10,11,7'-Trimethoxy-emetan-6'-ol,Hydrochlorid

AC1NUT82

CHEBI:2535

(2R,3R,11bS)-(+)-2-(3,4-dihydro-6-hydroxy-7-methoxy-1-isoquinolyl)methyl-3-ethyl-1,3,4,6,7,11b-hexahydro-8-hydroxy-9,10-dimethoxy-2H-benzo[a]quinolizine (alangicine)

Alangicine

7',10,11-Trimethoxyemetan-6'-ol dihydrochloride

2-(6-hydroxy-7-methoxy-3,4-dihydro-isoquinolin-1-ylmethyl)-3-ethyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-8-ol

Cephaeline dihydrochloride

10,11,7'-trimethoxy-emet-1'-ene-9,6'-diol

Emetan-6'-ol, 7',10,11-trimethoxy-, dihydrochloride (9CI)

10,11,7'-trimethoxy-emetan-6'-ol,dihydrochloride

(2R,3R,11bS)-3-ethyl-2-(6-hydroxy-7-methoxy-3,4-dihydroisoquinolin-1-ylmethyl)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-8-ol

6-Isoquinolinol, 1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-, (1R)-, hydrochloride (1:2)

10,11,7'-Trimethoxy-emetan-6'-ol,Dihydrochlorid

Emetan-6'-ol, 7',10,11-trimethoxy-, dihydrochloride