4-hydroxyisobenzofuran-1,3-dione

Modify Date: 2024-01-02 21:12:20

4-hydroxyisobenzofuran-1,3-dione Structure
4-hydroxyisobenzofuran-1,3-dione structure
Common Name 4-hydroxyisobenzofuran-1,3-dione
CAS Number 37418-88-5 Molecular Weight 164.12
Density 1.6±0.1 g/cm3 Boiling Point 365.4±25.0 °C at 760 mmHg
Molecular Formula C8H4O4 Melting Point 199-202 °C(lit.)
MSDS Chinese USA Flash Point 160.2±16.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 4-hydroxyisobenzofuran-1,3-dione


4-Hydroxyisobenzofuran-1,3-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 3-Hydroxyphthalic anhydride
Synonym More Synonyms

 4-hydroxyisobenzofuran-1,3-dione Biological Activity

Description 4-Hydroxyisobenzofuran-1,3-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 365.4±25.0 °C at 760 mmHg
Melting Point 199-202 °C(lit.)
Molecular Formula C8H4O4
Molecular Weight 164.12
Flash Point 160.2±16.7 °C
Exact Mass 164.010956
PSA 63.60000
LogP 0.86
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.666

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI3300000
CHEMICAL NAME :
Phthalic anhydride, 3-hydroxy-
CAS REGISTRY NUMBER :
37418-88-5
BEILSTEIN REFERENCE NO. :
0135783
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H4-O4
MOLECULAR WEIGHT :
164.12
WISWESSER LINE NOTATION :
T56 BVOVJ FQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#08845

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS TI3300000
HS Code 2932999099

 Synthetic Route

~70%

4-hydroxyisobenzofuran-1,3-dione Structure

4-hydroxyisoben...

CAS#:37418-88-5

Literature: Board of Trustees of Michigan State University Patent: US2005/267307 A1, 2005 ; Location in patent: Page/Page column 4 ;

~%

4-hydroxyisobenzofuran-1,3-dione Structure

4-hydroxyisoben...

CAS#:37418-88-5

Literature: Pratt; Perkins Journal of the American Chemical Society, 1918 , vol. 40, p. 230

~90%

4-hydroxyisobenzofuran-1,3-dione Structure

4-hydroxyisoben...

CAS#:37418-88-5

Literature: Nasman Synthesis, 1985 , vol. NO. 8, p. 788 - 789

~%

4-hydroxyisobenzofuran-1,3-dione Structure

4-hydroxyisoben...

CAS#:37418-88-5

Literature: Bentley; Robinson; Weizmann Journal of the Chemical Society, 1907 , vol. 91, p. 109

~%

4-hydroxyisobenzofuran-1,3-dione Structure

4-hydroxyisoben...

CAS#:37418-88-5

Literature: Bentley; Robinson; Weizmann Journal of the Chemical Society, 1907 , vol. 91, p. 109

~%

4-hydroxyisobenzofuran-1,3-dione Structure

4-hydroxyisoben...

CAS#:37418-88-5

Literature: Bentley; Robinson; Weizmann Journal of the Chemical Society, 1907 , vol. 91, p. 109

~%

4-hydroxyisobenzofuran-1,3-dione Structure

4-hydroxyisoben...

CAS#:37418-88-5

Literature: Bentley; Robinson; Weizmann Journal of the Chemical Society, 1907 , vol. 91, p. 109

~%

4-hydroxyisobenzofuran-1,3-dione Structure

4-hydroxyisoben...

CAS#:37418-88-5

Literature: Petfield; Amstutz Journal of Organic Chemistry, 1954 , vol. 19, p. 1944

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles5

More Articles
The antiviral activity of naturally occurring proteins and their peptide fragments after chemical modification.

Antiviral Res. 59(1) , 23-33, (2003)

Chemical modification of the proteins bovine serum albumin, alpha-lactalbumin, beta-lactoglobulin and chicken lysozyme by 3-hydroxyphthalic anhydride (3-HP) yielded compounds which exerted antiviral a...

[Antiviral activity of 3-hydroxyphthalic anhydride-modified ovalbumin against herpes simplex virus 2 in vitro].

Nan Fang Yi Ke Da Xue Xue Bao 31(7) , 1175-8, (2011)

To investigate the antiviral activity of 3-hydroxyphthalic anhydride-modified ovalbumin (HP-OVA) against herpes simplex virus 2 (HSV-2) in vitro.By chemical modification, ovalbumin (OVA) was treated w...

3-hydroxyphthalic anhydride-modified chicken ovalbumin exhibits potent and broad anti-HIV-1 activity: a potential microbicide for preventing sexual transmission of HIV-1.

Antimicrob. Agents Chemother. 54(5) , 1700-11, (2010)

Heterosexual transmission is the primary route by which women acquire human immunodeficiency virus (HIV)/AIDS. Thus, development of woman-controlled topical microbicides for prevention of sexual trans...

 Synonyms

MFCD00011557
3-Hydroxyphthalic anhydride
4-Hydroxyisobenzofuran-1,3-dione
4-Hydroxy-2-benzofuran-1,3-dione
1,3-Isobenzofurandione, 4-hydroxy-
4-Hydroxy-isobenzofuran-1,3-dione