5-(2-furylmethylidene)-3-phenyl-2-sulfanylidene-thiazolidin-4-one

Modify Date: 2026-08-19 23:04:57

5-(2-furylmethylidene)-3-phenyl-2-sulfanylidene-thiazolidin-4-one Structure
5-(2-furylmethylidene)-3-phenyl-2-sulfanylidene-thiazolidin-4-one structure
Common Name 5-(2-furylmethylidene)-3-phenyl-2-sulfanylidene-thiazolidin-4-one
CAS Number 37530-61-3 Molecular Weight 287.35700
Density 1.47g/cm3 Boiling Point 421.8ºC at 760 mmHg
Molecular Formula C14H9NO2S2 Melting Point N/A
MSDS N/A Flash Point 208.9ºC

 Names

Name (5E)-5-(furan-2-ylmethylidene)-3-phenyl-2-sulfanylidene-1,3-thiazolidin-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.47g/cm3
Boiling Point 421.8ºC at 760 mmHg
Molecular Formula C14H9NO2S2
Molecular Weight 287.35700
Flash Point 208.9ºC
Exact Mass 287.00700
PSA 90.84000
LogP 3.75040
Index of Refraction 1.745
InChIKey VXHVBXJIAJRGCB-FMIVXFBMSA-N
SMILES O=C1C(=Cc2ccco2)SC(=S)N1c1ccccc1

 Synthetic Route

~84%

5-(2-furylmethylidene)-3-phenyl-2-sulfanylidene-thiazolidin-4-one Structure

5-(2-furylmethy...

CAS#:37530-61-3

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Literature: Donia, Shaffy Galal Pakistan Journal of Scientific and Industrial Research, 1992 , vol. 35, # 12 p. 489 - 491

~%

5-(2-furylmethylidene)-3-phenyl-2-sulfanylidene-thiazolidin-4-one Structure

5-(2-furylmethy...

CAS#:37530-61-3

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Literature: Subenko; Turkewitsch Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 3275,3277; engl. Ausg. S. 3311

 Bioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: qHTS of TDP-43 Inhibitors: NCGC Sytravon Library Screen
Source: NCGC
External Id: tdp43-p2-repeat
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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 Synonyms

5-Furfuryliden-3-phenyl-2-thioxo-thiazolidin-4-on
5-Furan-2-ylmethylene-3-phenyl-2-thioxo-thiazolidin-4-one
HMS2557I23
5-furfurylidene-3-phenyl-2-thioxo-thiazolidin-4-one
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