Fenoverine

Modify Date: 2025-08-25 11:54:26

Fenoverine structure	Common Name	Fenoverine
	CAS Number	37561-27-6	Molecular Weight	459.56
	Density	1.343g/cm3	Boiling Point	671.8ºC at 760mmHg
	Molecular Formula	C₂₆H₂₅N₃O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	360.1ºC

Use of Fenoverine

Fenoverine is an antispasmodic drug and inhibits calcium channel currents[1]. Fenoverine induces rhabdomyolysis[2].

Name	2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-phenothiazin-10-ylethanone
Synonym	More Synonyms

Description	Fenoverine is an antispasmodic drug and inhibits calcium channel currents[1]. Fenoverine induces rhabdomyolysis[2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Neurological Disease
References	[1]. J Mironneau, et al. Fenoverine inhibition of calcium channel currents in single smooth muscle cells from rat portal vein and myometrium. Br J Pharmacol. 1991 Sep;104(1):65-70. [2]. Chung-Wen Chen, et al. Rhabdomyolysis induced by fenoverine: a case report and literature review. Acta Neurol Taiwan. 2005 Sep;14(3):143-6.

Description

Fenoverine is an antispasmodic drug and inhibits calcium channel currents[1]. Fenoverine induces rhabdomyolysis[2].

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Neurological Disease

References

[1]. J Mironneau, et al. Fenoverine inhibition of calcium channel currents in single smooth muscle cells from rat portal vein and myometrium. Br J Pharmacol. 1991 Sep;104(1):65-70.

[2]. Chung-Wen Chen, et al. Rhabdomyolysis induced by fenoverine: a case report and literature review. Acta Neurol Taiwan. 2005 Sep;14(3):143-6.

Density	1.343g/cm3
Boiling Point	671.8ºC at 760mmHg
Molecular Formula	C₂₆H₂₅N₃O₃S
Molecular Weight	459.56
Flash Point	360.1ºC
Exact Mass	459.16200
PSA	70.55000
LogP	4.30320
Index of Refraction	1.678
InChIKey	UBAJTZKNDCEGKL-UHFFFAOYSA-N
SMILES	O=C(CN1CCN(Cc2ccc3c(c2)OCO3)CC1)N1c2ccccc2Sc2ccccc21

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SN5445000

CHEMICAL NAME :: 10H-Phenothiazine, 10-((4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)ace tyl)-

CAS REGISTRY NUMBER :: 37561-27-6

LAST UPDATED :: 199312

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C26-H25-N3-O3-S

MOLECULAR WEIGHT :: 459.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2874 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 15,37,1989

Fenoverine

Spasmopriv

EINECS 253-552-1

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Fenoverine

Use of Fenoverine

Names

Fenoverine Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.