Clofoctol
Clofoctol structure
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Common Name | Clofoctol | ||
|---|---|---|---|---|
| CAS Number | 37693-01-9 | Molecular Weight | 365.33700 | |
| Density | 1.127 g/cm3 | Boiling Point | 447.7ºC at 760 mmHg | |
| Molecular Formula | C21H26Cl2O | Melting Point | 78° | |
| MSDS | Chinese USA | Flash Point | 160.4ºC | |
Use of ClofoctolClofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. It is only functional against Gram-positive bacteria, It penetrates into human lung tissue. |
| Name | 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol |
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| Synonym | More Synonyms |
| Description | Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. It is only functional against Gram-positive bacteria, It penetrates into human lung tissue. |
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| Related Catalog |
| Density | 1.127 g/cm3 |
|---|---|
| Boiling Point | 447.7ºC at 760 mmHg |
| Melting Point | 78° |
| Molecular Formula | C21H26Cl2O |
| Molecular Weight | 365.33700 |
| Flash Point | 160.4ºC |
| Exact Mass | 364.13600 |
| PSA | 20.23000 |
| LogP | 7.00360 |
| Index of Refraction | 1.555 |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 2 |
| RTECS | SL0533000 |
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Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer.
Br. J. Pharmacol. 171(19) , 4478-89, (2014) Finding new indications for existing drugs, also known as drug repositioning or repurposing, is a powerful approach to accelerate drug discovery and development. The unfolded protein response pathways... |
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A pharmacokinetic study of clofoctol in human plasma and lung tissue by using a microbiological assay.
Drugs Exp. Clin. Res. 14(1) , 39-43, (1988) A microbiological assay was undertaken to measure the amounts of clofoctol in human plasma and pulmonary tissue, and to investigate its pharmacokinetics. Clofoctol was extracted from samples using eth... |
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Alteration of membrane permeability in Bacillus subtilis by clofoctol.
J. Gen. Microbiol. 129(4) , 1089-95, (1983) When Bacillus subtilis was treated with a bacteriostatic concentration of clofoctol [2-(2,4-dichlorobenzyl)-4-(tetramethyl-1,1,3,3-butyl)phenol], UV-absorbing material was released. Electron micrograp... |
| EINECS 253-632-6 |
| 2-(2,4-Dichlorobenzyl)-4-(1,1,3,3-tetramethylbutyl)phenol |
| Clofoctolum |
| Octofene |
| clofoctol |