Rhodojaponin V

Modify Date: 2025-08-26 12:32:12

Rhodojaponin V structure	Common Name	Rhodojaponin V
	CAS Number	37720-86-8	Molecular Weight	410.501
	Density	1.4±0.1 g/cm3	Boiling Point	551.8±50.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₃₄O₇	Melting Point	232 °C
	MSDS	N/A	Flash Point	187.5±23.6 °C

Use of Rhodojaponin V

Rhodojaponin V is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity[1].

Name	Rhodojaponin V
Synonym	More Synonyms

Description	Rhodojaponin V is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Zhou J, et al. Anti-inflammatory Grayanane Diterpenoids from the Leaves of Rhododendron molle. J Nat Prod. 2018 Jan 26;81(1):151-161.

Density	1.4±0.1 g/cm3
Boiling Point	551.8±50.0 °C at 760 mmHg
Melting Point	232 °C
Molecular Formula	C₂₂H₃₄O₇
Molecular Weight	410.501
Flash Point	187.5±23.6 °C
Exact Mass	410.230438
PSA	119.75000
LogP	1.51
Vapour Pressure	0.0±3.4 mmHg at 25°C
Index of Refraction	1.603
InChIKey	OHDPFRGZBUACTR-UHFFFAOYSA-N
SMILES	CC(=O)OC1C2CCC3C(C)(O)C4C5OC5C(C)(C)C4(O)C(O)CC13CC2(C)O

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ME1110000

CHEMICAL NAME :: Grayanotoxane-5,6,10,14,16-pentol, 2,3-epoxy-, 14-acetate, (2-beta,3-beta,6-beta,14R)-

CAS REGISTRY NUMBER :: 37720-86-8

LAST UPDATED :: 199203

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C22-H34-O7

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 35,303,1976

Name: Cytotoxicity against mouse RAW264.7 cells at 200 uM measured in presence of LPS by MT...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL4136754

Name: Cytotoxicity against mouse RAW264.7 cells at 200 uM measured in absence of LPS by MTT...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL4136753

Name: Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL4136750

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5,6,10,16-Tetrahydroxy-2,3-epoxygrayanotoxan-14-yl acetate

Grayanotoxane-5,6,10,14,16-pentol, 2,3-epoxy-, 14-acetate