ACDPP Hydrochloride

Modify Date: 2024-01-24 07:25:15

ACDPP Hydrochloride structure	Common Name	ACDPP Hydrochloride
	CAS Number	37804-11-8	Molecular Weight	292.72
	Density	N/A	Boiling Point	473.6ºC at 760 mmHg
	Molecular Formula	C₁₂H₁₃ClN₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	240.3ºC

Use of ACDPP Hydrochloride

ACDPP is a specific mGluR5 antagonist. ACDPP partially bolcks the increase of fragile X mental retardation protein (FMRP) caused by DHPG (HY-12598A) (group I mGluR Agonist)[1].

Name	3-amino-6-chloro-5-(dimethylamino)-N-pyridin-3-ylpyrazine-2-carboxamide,hydrochloride

Description	ACDPP is a specific mGluR5 antagonist. ACDPP partially bolcks the increase of fragile X mental retardation protein (FMRP) caused by DHPG (HY-12598A) (group I mGluR Agonist)[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR5[1]
References	[1]. Wang H, et al. Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors. J Neurosci. 2008 Apr 23;28(17):4385-97.

Boiling Point	473.6ºC at 760 mmHg
Molecular Formula	C₁₂H₁₃ClN₆O
Molecular Weight	292.72
Flash Point	240.3ºC
Exact Mass	328.06100
PSA	97.03000
LogP	2.88170

2-Aminopyridine structure

2-Aminopyridine

CAS#:504-29-0

3-amino-6-chloro-5-dimethylamino-pyrazine-2-carboxylic acid structure

3-amino-6-chlor...

CAS#:27245-43-8

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ACDPP Hydrochloride Structure

ACDPP Hydrochloride

CAS#:37804-11-8

Literature: Bonnefous, Celine; Vernier, Jean-Michel; Hutchinson, John H.; Chung, Janice; Reyes-Manalo, Grace; Kamenecka, Theodore Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1197 - 1200

Precursor 2
CAS#:504-29-0 2-Aminopyridine CAS#:27245-43-8 3-amino-6-chlor...
DownStream 0

DC Chemicals Limited
China
Product Name: ACDPP Hydrochloride
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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