1-Tertbutyl piperazine

Modify Date: 2024-01-04 10:51:37

1-Tertbutyl piperazine Structure
1-Tertbutyl piperazine structure
Common Name 1-Tertbutyl piperazine
CAS Number 38216-72-7 Molecular Weight 142.242
Density 0.9±0.1 g/cm3 Boiling Point 185.0±8.0 °C at 760 mmHg
Molecular Formula C8H18N2 Melting Point N/A
MSDS Chinese USA Flash Point 57.2±9.4 °C

 Names

Name 1-(tert-Butyl)piperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 185.0±8.0 °C at 760 mmHg
Molecular Formula C8H18N2
Molecular Weight 142.242
Flash Point 57.2±9.4 °C
Exact Mass 142.147003
PSA 15.27000
LogP 1.05
Vapour Pressure 0.7±0.4 mmHg at 25°C
Index of Refraction 1.457

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 1-tert-butylpiperazine
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H314:Causes severe skin burns and eye damage
H400:Very toxic to aquatic life
P273:Avoid release to the environment
P280:Wear protective gloves/protective clothing/eye protection/face protection
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing
P310:Immediately call a POISON CENTER or doctor/physician

Section3. Composition/information on ingredients.
Ingredient name:1-tert-butylpiperazine
CAS number:38216-72-7

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
No data
Boiling point:
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C8H18N2
Molecular weight: 142.2

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes C
Risk Phrases 34
Safety Phrases 26-36/37/39-45
RIDADR 2735.0
Hazard Class 8.0
HS Code 2933599090

 Synthetic Route

~80%

1-Tertbutyl piperazine Structure

1-Tertbutyl pip...

CAS#:38216-72-7

Literature: NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2005/51366 A2, 2005 ; Location in patent: Page/Page column 69 ; WO 2005/051366 A2

~%

1-Tertbutyl piperazine Structure

1-Tertbutyl pip...

CAS#:38216-72-7

Literature: Sandoz, Inc. Patent: US3962248 A1, 1976 ;

~%

1-Tertbutyl piperazine Structure

1-Tertbutyl pip...

CAS#:38216-72-7

Literature: Poindexter, Graham S.; Bruce, Marc A.; LeBoulluec, Karen L.; Monkovic, Ivo Tetrahedron Letters, 1994 , vol. 35, # 40 p. 7331 - 7334

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

N-Tert-Butylpiperazine
1-Tertbutyl piperazine
1-tert-Butylpiperazine
1-T-butyl piperazine
1-(2-Methyl-2-propanyl)piperazine
Piperazine, 1-(1,1-dimethylethyl)-
MFCD00049359
Top Suppliers:I want be here



Get all suppliers and price by the below link:

1-Tertbutyl piperazine suppliers


Price: ¥38/250mg

Reference only. check more 1-Tertbutyl piperazine price