Dinoprost structure
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Common Name | Dinoprost | ||
|---|---|---|---|---|
| CAS Number | 38562-01-5 | Molecular Weight | 475.616 | |
| Density | N/A | Boiling Point | 531ºC at 760 mmHg | |
| Molecular Formula | C24H45NO8 | Melting Point | 25-35ºC | |
| MSDS | Chinese USA | Flash Point | 289ºC | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
Use of DinoprostDinoprost(Prostaglandin F2α) tromethamine salt is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. |
| Name | Prostaglandin F2α tris salt |
|---|---|
| Synonym | More Synonyms |
| Description | Dinoprost(Prostaglandin F2α) tromethamine salt is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. |
|---|---|
| Related Catalog | |
| References |
| Boiling Point | 531ºC at 760 mmHg |
|---|---|
| Melting Point | 25-35ºC |
| Molecular Formula | C24H45NO8 |
| Molecular Weight | 475.616 |
| Flash Point | 289ºC |
| Exact Mass | 475.314514 |
| PSA | 184.70000 |
| LogP | 1.40400 |
| Appearance of Characters | powder | white |
| InChIKey | IYGXEHDCSOYNKY-ZVJLOZNNSA-N |
| SMILES | CCCCCC(O)C=CC1C(O)CC(O)C1CC=CCCCC(=O)O.NC(CO)(CO)CO |
| Storage condition | −20°C |
| Water Solubility | H2O: 1 mg/mL Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at −0°C in single use aliquots. Avoid repeated freeze/thaw cycles. |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H360 |
| Precautionary Statements | P201-P280-P301 + P312 + P330-P308 + P313 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T: Toxic; |
| Risk Phrases | R60;R22 |
| Safety Phrases | 53-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | UK8025000 |
| HS Code | 2937500000 |
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Dinoprost CAS#:38562-01-5 |
| Literature: Aventis Pharma Deutschland GmbH Patent: US6399643 B1, 2002 ; |
|
~%
Dinoprost CAS#:38562-01-5 |
| Literature: Aventis Pharma Deutschland GmbH Patent: US6399643 B1, 2002 ; |
|
~%
Dinoprost CAS#:38562-01-5 |
| Literature: Aventis Pharma Deutschland GmbH Patent: US6399643 B1, 2002 ; |
|
~%
Dinoprost CAS#:38562-01-5 |
| Literature: Aventis Pharma Deutschland GmbH Patent: US6399643 B1, 2002 ; |
|
~%
Dinoprost CAS#:38562-01-5 |
| Literature: Aventis Pharma Deutschland GmbH Patent: US6399643 B1, 2002 ; |
| HS Code | 2937500000 |
|---|
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Efficient association between PGF2α and methyl 4-hydroxybenzoate sex pheromone prior to electroejaculation in dogs.
Reprod. Domest. Anim. 48(1) , 160-4, (2013) Electroejaculation is a technique that can be used to collect semen from canines, but its use with this group of animals is restricted by low success rate and low semen quality. Here, we evaluated whe... |
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In vitro comparison of myometrial contractility induced by aglepristone-oxytocin and aglepristone-PGF2alpha combinations at different stages of the estrus cycle in the bitch
Theriogenology 74 , 1531-8, (2010) The aim of this in vitro study was to compare the uterokinetic activity of oxytocin and dinoprost, the natural PGF2α, with or without aglepristone, in canine myometrial fibers. Thirty-three bitches we... |
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Compared to dinoprost tromethamine, cloprostenol sodium increased rates of estrus detection, conception and pregnancy in lactating dairy cows on a large commercial dairy.
Theriogenology 78(4) , 823-9, (2012) Using two PGF(2α) treatments 14 days apart as a way to enhance estrus detection rate following the 2nd treatment is a reproductive management tool that continues to be used on large dairy farms. In on... |
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL4296186
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Validation...
Source: NMMLSC
Target: ATP-binding cassette sub-family B member 6, mitochondrial [Homo sapiens]
External Id: UNMCMD_ABCB6_1o_ValidationSet
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| (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) |
| (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid - 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1) |
| Dinoprost trometamol |
| Prostaglandin F2a tromethamine |
| Prostaglandin F2-α tromethamine |
| Prostaglandin F2α tris salt |
| Prostaglandin F2a tris salt |
| PGF2-α tris salt |
| dinoprost, trometamol salt |
| Dinoprost Tromethamine |
| Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) |
| MFCD00077863 |
| 7-(3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-heptenoic Acid Tromethamine Salt |
| PGF2-α tromethamine |
| EINECS 254-002-3 |
| Lutalyse |
| Prostaglandin F(2)(α) tris salt |
| Prostaglandin F-2α tromethamine salt |
| Dinoprost compd. with 2-amino-2- (hydroxymethyl)-1,3-propanediol (1:1) |
| PGF2α−Tris |
| PGF2-α tromethamine salt |
| U 14583E |
| Dinoprost (tromethamine salt) |