3,4-Difluoroaniline
3,4-Difluoroaniline structure
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Common Name | 3,4-Difluoroaniline | ||
|---|---|---|---|---|
| CAS Number | 3863-11-4 | Molecular Weight | 129.107 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 205.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C6H5F2N | Melting Point | 22°C | |
| MSDS | Chinese USA | Flash Point | 85.0±0.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 3,4-Difluoroaniline |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 205.0±0.0 °C at 760 mmHg |
| Melting Point | 22°C |
| Molecular Formula | C6H5F2N |
| Molecular Weight | 129.107 |
| Flash Point | 85.0±0.0 °C |
| Exact Mass | 129.039001 |
| PSA | 26.02000 |
| LogP | 1.51 |
| Vapour Pressure | 0.3±0.4 mmHg at 25°C |
| Index of Refraction | 1.521 |
| InChIKey | AXNUZKSSQHTNPZ-UHFFFAOYSA-N |
| SMILES | Nc1ccc(F)c(F)c1 |
| Water Solubility | SLIGHTLY SOLUBLE |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R20/21/22;R36/37/38 |
| Safety Phrases | S26-S36-S36/37/39 |
| RIDADR | UN 2941 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | CX9871900 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 2921420090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 9 | |
CAS#:369-34-6
CAS#:7439-89-6
CAS#:85118-04-3
CAS#:5216-25-1
CAS#:2494-79-3
CAS#:62574-66-7
CAS#:127269-25-4
CAS#:371-40-4![1-(3,4-difluorophenyl)-7,7-dimethyl-3-[(3-nitrophenyl)methyl]-6,8-dihydroquinoline-2,5-dione structure](https://image.chemsrc.com/caspic/059/1065275-51-5.png)
CAS#:1065275-51-5
CAS#:60811-24-7
CAS#:144298-04-4
CAS#:42601-04-7
CAS#:205756-46-3
CAS#:194870-66-1
CAS#:169674-34-4
CAS#:221031-08-9
CAS#:2145-85-9This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2921420090 |
|---|---|
| Summary | HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Degradation of 3,4-dichloro- and 3,4-difluoroaniline by Pseudomonas fluorescens 26-K.
J. Environ. Sci. Health B 38(2) , 121-32, (2003) 3,4-Dichloro- and 3,4-difluoroanilines were degraded by Pseudomonas fluorescens 26-K under aerobic conditions. In the presence of glucose strain degraded 170 mg/L of 3,4-dichloroaniline (3,4-DCA) duri... |
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Synthesis and theoretical studies on the vibration of a novel (3,4-disfluoro)phenylquione.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 73(1) , 96-100, (2009) A novel (3,4-disfluoro)phenylquione (2F-PQ) was synthesized through the reaction of 3,4-Difluoroaniline and 1,4-benzoquinone. Its structure was verified by (1)H NMR, FTIR and Raman spectra. The ground... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Antiinflammatory activity in human monocytes assessed as inhibition of LPS-induced TN...
Source: ChEMBL
Target: Monocyte
External Id: CHEMBL4613793
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Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
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Name: Cytotoxicity against LPS-induced human monocytes assessed as cell viability at 50 uM ...
Source: ChEMBL
Target: Monocyte
External Id: CHEMBL4613797
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Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 3,4-fluoroaniline |
| ZR CF DF |
| 3',4'-difluoroaniline |
| EINECS 223-381-7 |
| 3,4-Difluoroaniline |
| 3,4-difluoro-benzenamin |
| 3,4-difluorophenylamine |
| 3,4-difluoraniline |
| Benzenamine,3,4-difluoro |
| 3,4-Difluorobenzenamine |
| MFCD00007761 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What English synonyms does 3,4-Difluoroaniline have? |
| A: English synonyms of 3,4-Difluoroaniline: 3,4-fluoroaniline, ZR CF DF, 3',4'-difluoroaniline, EINECS 223-381-7, 3,4-Difluoroaniline, 3,4-difluoro-benzenamin, 3,4-difluorophenylamine, 3,4-difluoraniline, Benzenamine,3,4-difluoro, 3,4-Difluorobenzenamine, MFCD00007761. |
| Q: What are the upstream materials of 3,4-Difluoroaniline? |
| A: Related upstream materials(CAS) of 3,4-Difluoroaniline: 369-34-6;7439-89-6;85118-04-3;5216-25-1;2494-79-3;62574-66-7;127269-25-4;371-40-4. |
| Q: What is the English name of 3,4-Difluoroaniline? |
| A: The English name of 3,4-Difluoroaniline is 3,4-Difluoroaniline. |
| Q: What is the InChIKey of 3,4-Difluoroaniline? |
| A: InChIKey of 3,4-Difluoroaniline is AXNUZKSSQHTNPZ-UHFFFAOYSA-N. |
| Q: What is the safety information for 3,4-Difluoroaniline? |
| A: Safety information for 3,4-Difluoroaniline: S26-S36-S36/37/39. |
| Q: What is the polar surface area (PSA) of 3,4-Difluoroaniline? |
| A: Polar surface area (PSA) of 3,4-Difluoroaniline is 26.02000. |
| Q: How is the water solubility of 3,4-Difluoroaniline? |
| A: Water solubility of 3,4-Difluoroaniline: SLIGHTLY SOLUBLE. |
| Q: What is the boiling point of 3,4-Difluoroaniline? |
| A: Boiling point of 3,4-Difluoroaniline is 205.0±0.0 °C at 760 mmHg. |
| Q: What is the LogP of 3,4-Difluoroaniline? |
| A: LogP of 3,4-Difluoroaniline is 1.51. |
| Q: What are the downstream products of 3,4-Difluoroaniline? |
| A: Related downstream products(CAS) of 3,4-Difluoroaniline: 1065275-51-5;60811-24-7;144298-04-4;42601-04-7;205756-46-3;194870-66-1;169674-34-4;221031-08-9;2145-85-9. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Dayang Chem (Hangzhou) Co., Ltd. |