Furobufen

Modify Date: 2025-08-25 20:51:49

Furobufen Structure
Furobufen structure
Common Name Furobufen
CAS Number 38873-55-1 Molecular Weight 268.26400
Density 1.343g/cm3 Boiling Point 509.8ºC at 760 mmHg
Molecular Formula C16H12O4 Melting Point N/A
MSDS N/A Flash Point 262.1ºC

 Use of Furobufen


Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue[1].

 Names

Name 4-dibenzofuran-2-yl-4-oxobutanoic acid
Synonym More Synonyms

 Furobufen Biological Activity

Description Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue[1].
Related Catalog
In Vivo Furobufen (po; 10, 30, 90 mg/kg; once daily; 7 days) produces a dose-related inhibition of the paw edema produced by carrageenan in male rats weighing 180-200 g[1].
References

[1]. Martel RR, et al. Anti-inflammatory properties of furobufen. Can J Physiol Pharmacol. 1974 Jun;52(3):669-73.

 Chemical & Physical Properties

Density 1.343g/cm3
Boiling Point 509.8ºC at 760 mmHg
Molecular Formula C16H12O4
Molecular Weight 268.26400
Flash Point 262.1ºC
Exact Mass 268.07400
PSA 67.51000
LogP 3.63350
Index of Refraction 1.676
InChIKey LQVMQEYROPXMQH-UHFFFAOYSA-N
SMILES O=C(O)CCC(=O)c1ccc2oc3ccccc3c2c1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HP4930000
CHEMICAL NAME :
2-Dibenzofuranbutanoic acid, gamma-oxo-
CAS REGISTRY NUMBER :
38873-55-1
BEILSTEIN REFERENCE NO. :
0250326
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H12-O4
MOLECULAR WEIGHT :
268.28
WISWESSER LINE NOTATION :
T B656 HOJ DV2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1283 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CJPPA3 Canadian Journal of Physiology and Pharmacology. (National Research Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.42- 1964- Volume(issue)/page/year: 52,669,1974

 Safety Information

HS Code 2932999099

 Synthetic Route

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Furobufen Structure

Furobufen

CAS#:38873-55-1

Literature: Mayer; Krieger Chemische Berichte, 1922 , vol. 55, p. 1664 Full Text Show Details Hoechster Farbw. Patent: DE376635 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 285 Full Text Show Details Krieger Diss. , S. 6, 14, 37

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Furobufen Structure

Furobufen

CAS#:38873-55-1

Literature: American Home Products Corporation Patent: US3985774 A1, 1976 ;

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-dibenzofuran-2-yl-4-oxo-butyric acid
Furobufenum [INN-Latin]
Furobufene [French]
Furobufeno [INN-Spanish]
Furobufen
Furobufeno [Spanish]
4-Dibenzofuran-2-yl-4-oxo-buttersaeure
Furobufene [INN-French]
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