22-Azacholesterol

Modify Date: 2024-02-27 18:46:24

22-Azacholesterol Structure
22-Azacholesterol structure
Common Name 22-Azacholesterol
CAS Number 3915-24-0 Molecular Weight 387.64200
Density N/A Boiling Point N/A
Molecular Formula C26H45NO Melting Point N/A
MSDS USA Flash Point N/A

 Use of 22-Azacholesterol


22-Azacholesterol is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells..

 Names

Name (3S,8S,9S,10R,13S,14S,17S)-10,13-dimethyl-17-[(1S)-1-(3-methylbutylamino)ethyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C26H45NO
Molecular Weight 387.64200
Exact Mass 387.35000
PSA 32.26000
LogP 6.34140

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

22-Azacholesterol