3915-24-0
3915-24-0 structure
- Name: 22-Azacholesterol
- Chemical Name: (3S,8S,9S,10R,13S,14S,17S)-10,13-dimethyl-17-[(1S)-1-(3-methylbutylamino)ethyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
- CAS Number: 3915-24-0
- Molecular Formula: C26H45NO
- Molecular Weight: 387.64200
- Create Date: 2017-06-20 03:36:58
- Modify Date: 2025-09-19 17:50:28
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22-Azacholesterol is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells..
| Name | (3S,8S,9S,10R,13S,14S,17S)-10,13-dimethyl-17-[(1S)-1-(3-methylbutylamino)ethyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol |
|---|---|
| Synonyms | 22-Azacholesterol |
| Molecular Formula | C26H45NO |
|---|---|
| Molecular Weight | 387.64200 |
| Exact Mass | 387.35000 |
| PSA | 32.26000 |
| LogP | 6.34140 |
| RIDADR | NONH for all modes of transport |
|---|