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3915-24-0

3915-24-0 structure
3915-24-0 structure
  • Name: 22-Azacholesterol
  • Chemical Name: (3S,8S,9S,10R,13S,14S,17S)-10,13-dimethyl-17-[(1S)-1-(3-methylbutylamino)ethyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • CAS Number: 3915-24-0
  • Molecular Formula: C26H45NO
  • Molecular Weight: 387.64200
  • Create Date: 2017-06-20 03:36:58
  • Modify Date: 2024-02-27 18:46:24
  • 22-Azacholesterol is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells..

Name (3S,8S,9S,10R,13S,14S,17S)-10,13-dimethyl-17-[(1S)-1-(3-methylbutylamino)ethyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Synonyms 22-Azacholesterol
Molecular Formula C26H45NO
Molecular Weight 387.64200
Exact Mass 387.35000
PSA 32.26000
LogP 6.34140
RIDADR NONH for all modes of transport