CAY10760

Modify Date: 2024-09-25 12:52:37

CAY10760 Structure
CAY10760 structure
Common Name CAY10760
CAS Number 391889-85-3 Molecular Weight 485.961
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C28H24ClN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CAY10760


Homologous recombination-IN-1 is a novel RAD51-BRCA2 protein-protein interaction inhibitor (EC50=19 μM). Homologous recombination-IN-1 can interfere with homologous recombination[1].

 Names

Name CAY10760
Synonym More Synonyms

 CAY10760 Biological Activity

Description Homologous recombination-IN-1 is a novel RAD51-BRCA2 protein-protein interaction inhibitor (EC50=19 μM). Homologous recombination-IN-1 can interfere with homologous recombination[1].
Related Catalog
In Vitro Homologous recombination-IN-1 (10-40 μM; 5 h) reduces cell homologous recombination in a dose-dependent manner[1]. Western Blot Analysis[1] Cell Line: BxPC3 cells Concentration: 10-40 μM Incubation Time: 5 hours Result: Led to homologous recombination inhibition with an EC50 value of 18.4 μM.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C28H24ClN3O3
Molecular Weight 485.961
Exact Mass 485.150604
LogP 4.39
Index of Refraction 1.660

 Synonyms

2(1H)-Quinolinone, 6-chloro-3-[4,5-dihydro-5-(4-methoxyphenyl)-1-(1-oxopropyl)-1H-pyrazol-3-yl]-4-phenyl-
CAY10760
6-Chloro-3-[5-(4-methoxyphenyl)-1-propionyl-4,5-dihydro-1H-pyrazol-3-yl]-4-phenyl-2(1H)-quinolinone