Methyl 4-fluoro-2-hydroxybenzoate

Modify Date: 2024-01-02 11:17:35

Methyl 4-fluoro-2-hydroxybenzoate Structure
Methyl 4-fluoro-2-hydroxybenzoate structure
Common Name Methyl 4-fluoro-2-hydroxybenzoate
CAS Number 392-04-1 Molecular Weight 170.138
Density 1.3±0.1 g/cm3 Boiling Point 224.7±20.0 °C at 760 mmHg
Molecular Formula C8H7FO3 Melting Point 38-40°C
MSDS N/A Flash Point 89.7±21.8 °C

 Names

Name Methyl 4-Fluoro-2-Hydroxybenzoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 224.7±20.0 °C at 760 mmHg
Melting Point 38-40°C
Molecular Formula C8H7FO3
Molecular Weight 170.138
Flash Point 89.7±21.8 °C
Exact Mass 170.037918
PSA 46.53000
LogP 2.71
Vapour Pressure 0.1±0.5 mmHg at 25°C
Index of Refraction 1.526
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
HS Code 2918290000

 Synthetic Route

~93%

Methyl 4-fluoro-2-hydroxybenzoate Structure

Methyl 4-fluoro...

CAS#:392-04-1

Literature: WYETH Patent: WO2005/12291 A1, 2005 ; Location in patent: Page/Page column 72 ; WO 2005/012291 A1

~98%

Methyl 4-fluoro-2-hydroxybenzoate Structure

Methyl 4-fluoro...

CAS#:392-04-1

Literature: ELI LILLY AND COMPANY Patent: WO2005/49604 A2, 2005 ; Location in patent: Page/Page column 40 ; WO 2005/049604 A2

~%

Methyl 4-fluoro-2-hydroxybenzoate Structure

Methyl 4-fluoro...

CAS#:392-04-1

Literature: Buchstaller, Hans-Peter; Eggenweiler, Hans-Michael; Sirrenberg, Christian; Graedler, Ulrich; Musil, Djordje; Hoppe, Edmund; Zimmermann, Astrid; Schwartz, Harry; Maerz, Joachim; Bomke, Joerg; Wegener, Ansgar; Wolf, Michael Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4396 - 4403

~89%

Methyl 4-fluoro-2-hydroxybenzoate Structure

Methyl 4-fluoro...

CAS#:392-04-1

Literature: Watanuki, Susumu; Matsuura, Keisuke; Tomura, Yuichi; Okada, Minoru; Okazaki, Toshio; Ohta, Mitsuaki; Tsukamoto, Shin-Ichi Chemical and Pharmaceutical Bulletin, 2012 , vol. 60, # 2 p. 223 - 234

~%

Methyl 4-fluoro-2-hydroxybenzoate Structure

Methyl 4-fluoro...

CAS#:392-04-1

Literature: Boyd, Derek R.; Sharma, Narain D.; Harrison, John S.; Malone, John. F.; McRoberts, W. Colin; Hamilton, John T. G.; Harper, David B. Organic and Biomolecular Chemistry, 2008 , vol. 6, # 7 p. 1251 - 1259

~%

Methyl 4-fluoro-2-hydroxybenzoate Structure

Methyl 4-fluoro...

CAS#:392-04-1

Literature: Boyd, Derek R.; Sharma, Narain D.; Harrison, John S.; Malone, John. F.; McRoberts, W. Colin; Hamilton, John T. G.; Harper, David B. Organic and Biomolecular Chemistry, 2008 , vol. 6, # 7 p. 1251 - 1259

~%

Methyl 4-fluoro-2-hydroxybenzoate Structure

Methyl 4-fluoro...

CAS#:392-04-1

Literature: SYNTA PHARMACEUTICALS CORP.; CHIMMANAMADA, Dinesh; DEMKO, Zachary; YING, Weiwen Patent: WO2013/148857 A1, 2013 ;

 Customs

HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

 Synonyms

Methyl 4-fluoro-2-hydroxybenzoate
Benzoic acid, 4-fluoro-2-hydroxy-, methyl ester
Methyl 4-fluorosalicylate
MFCD02093965
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