1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine

Modify Date: 2024-01-14 18:06:46

1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine Structure
1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine structure
Common Name 1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
CAS Number 393845-24-4 Molecular Weight 321.419
Density 1.2±0.1 g/cm3 Boiling Point 447.5±45.0 °C at 760 mmHg
Molecular Formula C19H23N5 Melting Point N/A
MSDS N/A Flash Point 224.4±28.7 °C

 Use of 1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine


VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 μM[1].

 Names

Name VU0080241
Synonym More Synonyms

  Biological Activity

Description VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 μM[1].
Related Catalog
Target

mGlu4:4.6 μM (EC50)

References

[1]. Colleen M Niswender, et al. Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Bioorg Med Chem Lett. 2008 Oct 15; 18(20): 5626-5630.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 447.5±45.0 °C at 760 mmHg
Molecular Formula C19H23N5
Molecular Weight 321.419
Flash Point 224.4±28.7 °C
Exact Mass 321.195343
LogP 4.41
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.672

 Synonyms

1-(2,4-Dimethylphenyl)-4-(3-methyl-1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine
VU0080241
1H-Pyrazolo[3,4-d]pyrimidine, 1-(2,4-dimethylphenyl)-4-(3-methyl-1-piperidinyl)-
MFCD03474901
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Price: ¥1650/10 mM * 1 mL in DMSO

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