Bis-isopropyl-PEG1

Modify Date: 2024-01-10 05:06:31

Bis-isopropyl-PEG1 Structure
Bis-isopropyl-PEG1 structure
Common Name Bis-isopropyl-PEG1
CAS Number 3944-35-2 Molecular Weight 146.22700
Density 0.84g/cm3 Boiling Point 148.2ºC at 760mmHg
Molecular Formula C8H18O2 Melting Point N/A
MSDS N/A Flash Point 26ºC

 Use of Bis-isopropyl-PEG1


Bis-isopropyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-(2-propan-2-yloxyethoxy)propane
Synonym More Synonyms

 Bis-isopropyl-PEG1 Biological Activity

Description Bis-isopropyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 0.84g/cm3
Boiling Point 148.2ºC at 760mmHg
Molecular Formula C8H18O2
Molecular Weight 146.22700
Flash Point 26ºC
Exact Mass 146.13100
PSA 18.46000
LogP 1.83640
Index of Refraction 1.403

 Safety Information

HS Code 2909199090

 Customs

HS Code 2909199090
Summary 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

1,2-Diisopropoxy-aethan
2-(2-isopropoxyethoxy)propane
2,2'-[ETHYLENEBIS(OXY)]BISPROPANE
1,2-diisopropoxy-ethane
EINECS 223-532-7