Bis-isopropyl-PEG1

Modify Date: 2025-09-22 23:32:30

Bis-isopropyl-PEG1 Structure
Bis-isopropyl-PEG1 structure
Common Name Bis-isopropyl-PEG1
CAS Number 3944-35-2 Molecular Weight 146.22700
Density 0.84g/cm3 Boiling Point 148.2ºC at 760mmHg
Molecular Formula C8H18O2 Melting Point N/A
MSDS N/A Flash Point 26ºC

 Use of Bis-isopropyl-PEG1


Bis-isopropyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-(2-propan-2-yloxyethoxy)propane
Synonym More Synonyms

 Bis-isopropyl-PEG1 Biological Activity

Description Bis-isopropyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 0.84g/cm3
Boiling Point 148.2ºC at 760mmHg
Molecular Formula C8H18O2
Molecular Weight 146.22700
Flash Point 26ºC
Exact Mass 146.13100
PSA 18.46000
LogP 1.83640
Index of Refraction 1.403
InChIKey MGZCLRWCEUBEGO-UHFFFAOYSA-N
SMILES CC(C)OCCOC(C)C

 Safety Information

HS Code 2909199090

 Customs

HS Code 2909199090
Summary 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

1,2-Diisopropoxy-aethan
2-(2-isopropoxyethoxy)propane
2,2'-[ETHYLENEBIS(OXY)]BISPROPANE
1,2-diisopropoxy-ethane
EINECS 223-532-7
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