(2S)-Methoxy(phenyl)acetic acid

Modify Date: 2024-01-04 17:07:52

(2S)-Methoxy(phenyl)acetic acid Structure
(2S)-Methoxy(phenyl)acetic acid structure
Common Name (2S)-Methoxy(phenyl)acetic acid
CAS Number 3966-32-3 Molecular Weight 166.174
Density 1.2±0.1 g/cm3 Boiling Point 283.8±0.0 °C at 760 mmHg
Molecular Formula C9H10O3 Melting Point 64-67ºC
MSDS Chinese USA Flash Point 116.1±15.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name (R)-(-)-alpha-Methoxyphenylacetic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 283.8±0.0 °C at 760 mmHg
Melting Point 64-67ºC
Molecular Formula C9H10O3
Molecular Weight 166.174
Flash Point 116.1±15.3 °C
Exact Mass 166.062988
PSA 46.53000
LogP 1.29
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.535

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918990090

 Synthetic Route

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles5

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Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.

Bioorg. Med. Chem. 22(17) , 4968-97, (2014)

TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led t...

B.M. Trost et al.

J. Org. Chem. 51 , 2370, (1986)

J. Org. Chem. 59 , 4202, (1994)

 Synonyms

(R)-(-)-α-Methoxyphenylacetic acid
(2S)-Methoxy(phenyl)acetic acid
(R)-2-Methoxy-2-phenylacetic acid
(R)-(-)-alpha-Methoxyphenylacetic Acid
Benzeneacetic acid, α-methoxy-, (αR)-
EINECS 223-580-9
(2R)-methoxy(phenyl)ethanoic acid
MFCD00004250
(2R)-Methoxy(phenyl)acetic acid
Benzeneacetic acid, α-methoxy-, (αS)-
Benzeneacetic acid, α-methoxy-, (S)-
Benzeneacetic acid, α-methoxy-, (R)-
(2S)-methoxy(phenyl)ethanoic acid