SDZ 21009

Modify Date: 2025-08-26 20:52:15

SDZ 21009 structure	Common Name	SDZ 21009
	CAS Number	39731-05-0	Molecular Weight	348.44
	Density	1.15g/cm3	Boiling Point	529.8ºC at 760mmHg
	Molecular Formula	C₁₉H₂₈N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	274.2ºC

Use of SDZ 21009

Carpindolol (SDZ21009) is a 5-HT1B receptor antagonist (pKd of 8.53 and pKB of 8.0) and a 5-HT1D receptor agonist (pEC50 of 5.91 and pKd of 6.37)[1].

Name	propan-2-yl 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylate

Description	Carpindolol (SDZ21009) is a 5-HT1B receptor antagonist (pKd of 8.53 and pKB of 8.0) and a 5-HT1D receptor agonist (pEC50 of 5.91 and pKd of 6.37)[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT1B Receptor:8.53 (pKd) 5-HT1D Receptor:5.91 (pEC50) 5-HT1D Receptor:6.37 (pKd)
References	[1]. P Schoeffter, et al. 5-Hydroxytryptamine 5-HT1B and 5-HT1D receptors mediating inhibition of adenylate cyclase activity. Pharmacological comparison with special reference to the effects of yohimbine, rauwolscine and some beta-adrenoceptor antagonists. Naunyn Schmiedebergs Arch Pharmacol. 1989 Sep;340(3):285-92.

Density	1.15g/cm3
Boiling Point	529.8ºC at 760mmHg
Molecular Formula	C₁₉H₂₈N₂O₄
Molecular Weight	348.44
Flash Point	274.2ºC
Exact Mass	348.20500
PSA	83.58000
LogP	3.25180
Index of Refraction	1.567
InChIKey	SJYFDORQYYEJLB-UHFFFAOYSA-N
SMILES	CC(C)OC(=O)c1cc2c(OCC(O)CNC(C)(C)C)cccc2[nH]1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SDZ 21009
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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