5-Fluoronicotinic acid

Modify Date: 2024-01-02 22:44:31

5-Fluoronicotinic acid Structure
5-Fluoronicotinic acid structure
Common Name 5-Fluoronicotinic acid
CAS Number 402-66-4 Molecular Weight 141.100
Density 1.4±0.1 g/cm3 Boiling Point 272.2±20.0 °C at 760 mmHg
Molecular Formula C6H4FNO2 Melting Point 199 °C
MSDS USA Flash Point 118.4±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 5-Fluoronicotinic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 272.2±20.0 °C at 760 mmHg
Melting Point 199 °C
Molecular Formula C6H4FNO2
Molecular Weight 141.100
Flash Point 118.4±21.8 °C
Exact Mass 141.022614
PSA 50.19000
LogP 0.41
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.542

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US5745250
CHEMICAL NAME :
3-Pyridinecarboxylic acid, 5-fluoro-
CAS REGISTRY NUMBER :
402-66-4
LAST UPDATED :
199806
DATA ITEMS CITED :
1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3737542

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39
RIDADR NONH for all modes of transport
RTECS US5745250
HS Code 2942000000

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles2

More Articles
Pyridonecarboxylic acids as antibacterial agents. VIII. An alternative synthesis of enoxacin via fluoronicotinic acid derivatives.

Chem. Pharm. Bull. 35(6) , 2280-5, (1987)

Hydrophobic chromatography and bioanalysis of some polar pyridine derivatives used as antilipolytic agents.

J. Chromatogr. A. 187(1) , 189-98, (1980)

The antilipolytic compound 5-fluoro-3-pyridinecarboxylic acid and 5-fluoro-3-hydroxymethylpyridine have been determined quantitatively in plasma (Srel = 5-7% in the concentration range 1-20 microgram/...

 Synonyms

MFCD01318537
Nicotinic acid, 5-fluoro-
T6NJ CVQ EF
5-Fluoronicotinic acid
5-Fluoropyridine-3-carboxylic acid
5-Fluoro-3-pyridinecarboxylic acid
3-Pyridinecarboxylic acid, 5-fluoro-
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