1-Cyclohexyl-3-dodecyl urea
Modify Date: 2024-01-27 14:27:55
1-Cyclohexyl-3-dodecyl urea structure
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Common Name | 1-Cyclohexyl-3-dodecyl urea | ||
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| CAS Number | 402939-18-8 | Molecular Weight | 310.51800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H38N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 1-Cyclohexyl-3-dodecyl urea1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) is a highly selective soluble epoxide hydrolase (sEH) inhibitor. 1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) increases epoxyeicosatrienoic acids (EETs) levels and lowers blood pressure in angiotensin II (Ang II) hypertension[1]. |
| Name | 1-cyclohexyl-3-dodecylurea |
|---|---|
| Synonym | More Synonyms |
| Description | 1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) is a highly selective soluble epoxide hydrolase (sEH) inhibitor. 1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) increases epoxyeicosatrienoic acids (EETs) levels and lowers blood pressure in angiotensin II (Ang II) hypertension[1]. |
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| Related Catalog | |
| Target |
IC50: soluble epoxide hydrolase (sEH)[1] |
| In Vivo | 1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) ( intraperitoneal injection; 3mg/day; 4 days) lowers systolic blood pressure by 30 mm Hg in Ang II hypertensive animals, whereas the corn oil vehicle has no effect on blood pressure in normotensive or Ang II hypertensive animals[1]. Animal Model: Male Sprague-Dawley rats[1] Dosage: 3mg/day Administration: Intraperitoneal injection; 4 days Result: Had antihypertensive properties. |
| References |
| Molecular Formula | C19H38N2O |
|---|---|
| Molecular Weight | 310.51800 |
| Exact Mass | 310.29800 |
| PSA | 44.62000 |
| LogP | 6.13450 |
| Storage condition | 2-8℃ |
| Urea,N-cyclohexyl-N'-dodecyl |
| Soluble Epoxide Hydrolase Inhibitor,NCND |