Thalidomide-5-methyl

Modify Date: 2025-08-26 19:09:24

Thalidomide-5-methyl Structure
Thalidomide-5-methyl structure
 Common Name Thalidomide-5-methyl
CAS Number 40313-92-6 Molecular Weight 272.26
Density N/A Boiling Point N/A
Molecular Formula C14H12N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-5-methyl


Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].

 Names

Name Thalidomide-5-methyl

 Thalidomide-5-methyl Biological Activity

Description Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. George W. Muller, et al. Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels. Patent US5874448A.

 Chemical & Physical Properties

Molecular Formula C14H12N2O4
Molecular Weight 272.26
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Chemsrc provides Thalidomide-5-methyl(CAS#:40313-92-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Thalidomide-5-methyl are included as well.>> amp version: Thalidomide-5-methyl

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