Thalidomide-5-methyl

Modify Date: 2024-01-03 11:06:15

Thalidomide-5-methyl structure	Common Name	Thalidomide-5-methyl
	CAS Number	40313-92-6	Molecular Weight	272.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₂N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thalidomide-5-methyl

Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].

Name	Thalidomide-5-methyl

Description	Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. George W. Muller, et al. Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels. Patent US5874448A.

Molecular Formula	C₁₄H₁₂N₂O₄
Molecular Weight	272.26

DC Chemicals Limited
China
Product Name: Thalidomide-5-methyl
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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