1-benzyl-4-nitrosopiperazine

Modify Date: 2024-01-11 12:19:25

1-benzyl-4-nitrosopiperazine Structure
1-benzyl-4-nitrosopiperazine structure
Common Name 1-benzyl-4-nitrosopiperazine
CAS Number 40675-45-4 Molecular Weight 205.25600
Density 1.16g/cm3 Boiling Point 350.6ºC at 760mmHg
Molecular Formula C11H15N3O Melting Point 56-58ºC
MSDS N/A Flash Point 165.8ºC

 Names

Name 1-benzyl-4-nitrosopiperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.16g/cm3
Boiling Point 350.6ºC at 760mmHg
Melting Point 56-58ºC
Molecular Formula C11H15N3O
Molecular Weight 205.25600
Flash Point 165.8ºC
Exact Mass 205.12200
PSA 35.91000
LogP 1.36140
Index of Refraction 1.595

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TK8379000
CHEMICAL NAME :
Piperazine, 1-benzyl-4-nitroso-
CAS REGISTRY NUMBER :
40675-45-4
BEILSTEIN REFERENCE NO. :
0172918
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H15-N3-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,280,1968

 Safety Information

HS Code 2933599090

 Synthetic Route

~34%

1-benzyl-4-nitrosopiperazine Structure

1-benzyl-4-nitr...

CAS#:40675-45-4

Literature: KARYOPHARM THERAPEUTICS, INC.; SANDANAYAKA, Vincent, P.; SHACHAM, Sharon; MCCAULEY, Dilara; SHECHTER, Sharon Patent: WO2013/19548 A1, 2013 ; Location in patent: Page/Page column 73 ; WO 2013/019548 A1

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1-benzyl-4-nitrosopiperazine Structure

1-benzyl-4-nitr...

CAS#:40675-45-4

Literature: Manetti, Dina; Mannelli, Lorenzo Di Cesare; Dei, Silvia; Galeotti, Nicoletta; Ghelardini, Carla; Romanelli, Maria Novella; Scapecchi, Serena; Teodori, Elisabetta; Pacini, Alessandra; Bartolini, Alessandro; Gualtieri, Fulvio Journal of Medicinal Chemistry, 2005 , vol. 48, # 20 p. 6491 - 6503

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1-benzyl-4-nitrosopiperazine Structure

1-benzyl-4-nitr...

CAS#:40675-45-4

Literature: Zhang, Yinsheng; Stolle, Wayne T. Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 5-6 p. 487 - 489

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-nitroso-4-benzylpiperazine
4-Benzyl-1-nitroso-piperazin
N-nitroso-N-benzylpiperazine
1-benzyl-4-nitroso-4-piperizine
1-benzyl-4-nitroso-piperazine
Piperazine,1-benzyl-4-nitroso
4-nitroso-1-benzylpiperazine
N1-Benzyl-N4-nitroso-piperazin
1-Benzyl-4-nitroso-piperazin