1-Nitrosopiperazine

Modify Date: 2025-08-27 22:49:05

1-Nitrosopiperazine Structure
1-Nitrosopiperazine structure
Common Name 1-Nitrosopiperazine
CAS Number 5632-47-3 Molecular Weight 115.134
Density 1.3±0.1 g/cm3 Boiling Point 264.5±33.0 °C at 760 mmHg
Molecular Formula C4H9N3O Melting Point N/A
MSDS N/A Flash Point 113.8±25.4 °C

 Names

Name N-Nitrosopiperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 264.5±33.0 °C at 760 mmHg
Molecular Formula C4H9N3O
Molecular Weight 115.134
Flash Point 113.8±25.4 °C
Exact Mass 115.074562
PSA 44.70000
LogP 0.18
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.602

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TM2450000
CHEMICAL NAME :
Piperazine, 1-nitroso-
CAS REGISTRY NUMBER :
5632-47-3
BEILSTEIN REFERENCE NO. :
0112147
LAST UPDATED :
199612
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C4-H9-N3-O
MOLECULAR WEIGHT :
115.16
WISWESSER LINE NOTATION :
T6M DNTJ DNO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2260 mg/kg
TOXIC EFFECTS :
Brain and Coverings - changes in circulation (hemorrhage, thrombosis, etc.) Lungs, Thorax, or Respiration - acute pulmonary edema Liver - fatty liver degeneration
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5400 mg/kg/60W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Reproductive - Tumorigenic effects - uterine tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
720 mg/kg/20W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1400 mg/kg/60W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Liver - tumors Blood - tumors

MUTATION DATA

TYPE OF TEST :
Host-mediated assay
TEST SYSTEM :
Rodent - mouse Bacteria - Escherichia coli
DOSE/DURATION :
150 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 272,161,1992

 Synthetic Route

 Synonyms

1-Nitrosopiperazine
Piperazine, 1-nitroso-
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