(4-Biphenyl)Acetamide

Modify Date: 2025-08-27 21:18:57

(4-Biphenyl)Acetamide Structure
(4-Biphenyl)Acetamide structure
Common Name (4-Biphenyl)Acetamide
CAS Number 4075-79-0 Molecular Weight 211.259
Density 1.1±0.1 g/cm3 Boiling Point 419.3±24.0 °C at 760 mmHg
Molecular Formula C14H13NO Melting Point 172ºC
MSDS N/A Flash Point 251.4±7.8 °C

 Names

Name N-Acetyl-4-aminobiphenyl
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 419.3±24.0 °C at 760 mmHg
Melting Point 172ºC
Molecular Formula C14H13NO
Molecular Weight 211.259
Flash Point 251.4±7.8 °C
Exact Mass 211.099716
PSA 29.10000
LogP 3.14
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.610

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AE6125000
CHEMICAL NAME :
Acetanilide, 4'-phenyl-
CAS REGISTRY NUMBER :
4075-79-0
BEILSTEIN REFERENCE NO. :
2097736
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C14-H13-N-O
MOLECULAR WEIGHT :
211.28
WISWESSER LINE NOTATION :
1VMR DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2770 mg/kg/21W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Skin and Appendages - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
13 gm/kg/3Y-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4070 mg/kg/34W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Skin and Appendages - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3425 mg/kg/26W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2240 mg/kg/16W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
10 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 175,11,1986 *** REVIEWS *** TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970

 Safety Information

HS Code 2924299090

 Synthetic Route

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 (4-Biphenyl)AcetamideBioassay

View more

Name: Compound was tested for carcinogenic activity on mixed data after oral administration...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL771341
Name: Carcinogenic activity on breast after oral administration of the compound
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL770577
Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Carcinogenic activity on other sites after oral administration
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL772506
Name: ASTRAZENECA: Solubility in pH7.4 buffer using solid starting material using the metho...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3301364
Name: Carcinogenesis bioassays from the Carcinogenic Potency Database (CPDB)
Source: 25294
Target: N/A
External Id: cpdb
Name: Inhibition of AHAT-catalyzed transacylation of 4-aminoazobenzene
Source: ChEMBL
Target: N/A
External Id: CHEMBL747006
Name: Carcinogenic activity on ear duct after oral administration
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL771496
Name: Compound was tested for carcinogenic activity on liver after oral administration of t...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL771453
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 Synonyms

N-[1,1'-biphenyl]-4-ylacetamide
4-acetylaminobiphenyl
N-(4-Biphenylyl)acetamide
N-(4-phenylphenyl)acetamide
N-BIPHENYL-4-YL-ACETAMIDE
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