thiadiazole-4-carboxamide

Modify Date: 2026-07-01 20:02:38

thiadiazole-4-carboxamide Structure
thiadiazole-4-carboxamide structure
Common Name thiadiazole-4-carboxamide
CAS Number 4100-20-3 Molecular Weight 129.14000
Density 1.536g/cm3 Boiling Point 370.2ºC at 760 mmHg
Molecular Formula C3H3N3OS Melting Point 216ºC
MSDS N/A Flash Point 177.7ºC

Summary: Chinese name: 1,2,3-thiadiazole-4-carboxamide, English name: thiadiazole-4-carboxamide, CAS number: 4100-20-3, molecular formula: C3H3N3OS, molecular weight: 129.14000. The melting point is 216ºC, boiling point is 370.2ºC, and density is 1.536g/cm3. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name thiadiazole-4-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.536g/cm3
Boiling Point 370.2ºC at 760 mmHg
Melting Point 216ºC
Molecular Formula C3H3N3OS
Molecular Weight 129.14000
Flash Point 177.7ºC
Exact Mass 129.00000
PSA 97.11000
LogP 0.33730
Index of Refraction 1.625
InChIKey INWVNNCOIIHEPX-UHFFFAOYSA-N
SMILES NC(=O)c1csnn1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Name: 1 2 3-Thiadiazole-4-carboxamide 97% Material Safety Data Sheet
Synonym:
CAS: 4100-20-3
Section 1 - Chemical Product MSDS Name:1 2 3-Thiadiazole-4-carboxamide 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
4100-20-3 1,2,3-Thiadiazole-4-carboxamide 97% unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 4100-20-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 216 - 218 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C3H3N3OS
Molecular Weight: 129.14

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 4100-20-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1,2,3-Thiadiazole-4-carboxamide - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 4100-20-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 4100-20-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 4100-20-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Safety Phrases S24/25
HS Code 2934999090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~70%

thiadiazole-4-carboxamide Structure

thiadiazole-4-c...

CAS#:4100-20-3

Learn More
Literature: Li, Zaifeng; Wu, Zengru; Luo, Fuying Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 10 p. 3872 - 3876

~%

thiadiazole-4-carboxamide Structure

thiadiazole-4-c...

CAS#:4100-20-3

Learn More
Literature: Looker,J.H.; Wilson,L.W. Journal of Heterocyclic Chemistry, 1965 , vol. 2, p. 348 - 354

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  2

DownStream  0

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

1,2,3-Thiadiazol-4-carboxyamid
[1,2,3]thiadiazole-4-carboxylic acid amide
4-Carbamoyl-1,2,3-thiadiazol

 thiadiazole-4-carboxamide | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the LogP of thiadiazole-4-carboxamide?
A: LogP of thiadiazole-4-carboxamide is 0.33730.
Q: What is the boiling point of thiadiazole-4-carboxamide?
A: Boiling point of thiadiazole-4-carboxamide is 370.2ºC at 760 mmHg.
Q: What is the molecular formula of thiadiazole-4-carboxamide?
A: Molecular formula of thiadiazole-4-carboxamide is C3H3N3OS.
Q: What is the SMILES notation of thiadiazole-4-carboxamide?
A: SMILES notation of thiadiazole-4-carboxamide is NC(=O)c1csnn1.
Q: What is the InChIKey of thiadiazole-4-carboxamide?
A: InChIKey of thiadiazole-4-carboxamide is INWVNNCOIIHEPX-UHFFFAOYSA-N.
Q: What English synonyms does thiadiazole-4-carboxamide have?
A: English synonyms of thiadiazole-4-carboxamide: 1,2,3-Thiadiazol-4-carboxyamid, [1,2,3]thiadiazole-4-carboxylic acid amide, 4-Carbamoyl-1,2,3-thiadiazol.
Q: What is the polar surface area (PSA) of thiadiazole-4-carboxamide?
A: Polar surface area (PSA) of thiadiazole-4-carboxamide is 97.11000.
Q: What is the safety information for thiadiazole-4-carboxamide?
A: Safety information for thiadiazole-4-carboxamide: S24/25.
Q: What is the English name of thiadiazole-4-carboxamide?
A: The English name of thiadiazole-4-carboxamide is thiadiazole-4-carboxamide.
Q: What is the molecular weight of thiadiazole-4-carboxamide?
A: Molecular weight of thiadiazole-4-carboxamide is 129.14000.

 thiadiazole-4-carboxamidefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Dayang Chem (Hangzhou) Co., Ltd.
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