Hirsutal

Modify Date: 2024-01-10 10:53:58

Hirsutal Structure
Hirsutal structure
 Common Name Hirsutal
CAS Number 41137-86-4 Molecular Weight 346.374
Density 1.4±0.1 g/cm3 Boiling Point 679.6±55.0 °C at 760 mmHg
Molecular Formula C19H22O6 Melting Point N/A
MSDS N/A Flash Point 378.8±28.0 °C

 Use of Hirsutal


Hirsutanonol ((5S)-Hirsutanonol) is a diarylheptanoid that can be isolated from the bark of Alnus hirsute var. sibirica. Hirsutanonol inhibits cyclooxygenase-2 (COX-2) expression. Hirsutanonol has anti-filarial with an IC50 value of 44.11 μg/mL for microfilariae[1].

 Names

Name (5S)-1,7-Bis(3,4-dihydroxyphenyl)-5-hydroxy-3-heptanone
Synonym More Synonyms

 Hirsutal Biological Activity

Description Hirsutanonol ((5S)-Hirsutanonol) is a diarylheptanoid that can be isolated from the bark of Alnus hirsute var. sibirica. Hirsutanonol inhibits cyclooxygenase-2 (COX-2) expression. Hirsutanonol has anti-filarial with an IC50 value of 44.11 μg/mL for microfilariae[1].
Related Catalog
References

[1]. Lee MW, et al. Inhibition of cyclooxygenase-2 expression by diarylheptanoids from the bark of Alnus hirsuta var. sibirica. Biol Pharm Bull. 2000 Apr;23(4):517-8.  

[2]. Yadav D, et al. Antifilarial diarylheptanoids from Alnus nepalensis leaves growing in high altitude areas of Uttarakhand, India. Phytomedicine. 2013 Jan 15;20(2):124-32.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 679.6±55.0 °C at 760 mmHg
Molecular Formula C19H22O6
Molecular Weight 346.374
Flash Point 378.8±28.0 °C
Exact Mass 346.141632
PSA 118.22000
LogP 0.88
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.648

 Safety Information

HS Code 2914501900

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2914501900
Summary 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

hirsutanonol
7,7-diphenyl-4,5,6,6a-tetrahydro-1H,3H-pyrrolo<1,2-c>oxazol-2-one
(5S)-1,7-Bis(3,4-dihydroxyphenyl)-5-hydroxy-3-heptanone
3-Heptanone, 1,7-bis(3,4-dihydroxyphenyl)-5-hydroxy-, (5S)-
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