Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside

Modify Date: 2024-01-02 11:00:08

Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside Structure
Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside structure
Common Name Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside
CAS Number 4137-56-8 Molecular Weight 358.41
Density 1.3±0.1 g/cm3 Boiling Point 475.3±45.0 °C at 760 mmHg
Molecular Formula C16H22O7S Melting Point 83-84ºC
MSDS Chinese USA Flash Point 241.3±28.7 °C

 Use of Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside


Methyl 2,3-O-isopropylidene-5-O-tosyl-D-ribonucleoside is a biochemical reagent that can be used for compound synthesis[1].

 Names

Name Methyl 2,3-O-Isopropylidene-5-O-p-tolylsulfonyl--D-ribofuranoside
Synonym More Synonyms

  Biological Activity

Description Methyl 2,3-O-isopropylidene-5-O-tosyl-D-ribonucleoside is a biochemical reagent that can be used for compound synthesis[1].
Related Catalog
References

[1]. Shingare RD, et al. Antibiotic natural product hunanamycin A: Lead identification towards anti-Salmonella agents. Eur J Med Chem. 2022 Jun 5;236:114245.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 475.3±45.0 °C at 760 mmHg
Melting Point 83-84ºC
Molecular Formula C16H22O7S
Molecular Weight 358.41
Flash Point 241.3±28.7 °C
Exact Mass 358.108612
PSA 88.67000
LogP 2.24
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.555
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~98%

Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside Structure

Methyl 2,3-O-is...

CAS#:4137-56-8

Literature: Sarabia-Garcia, Francisco; Lopez-Herrera, F. Jorge Tetrahedron, 1996 , vol. 52, # 13 p. 4757 - 4768

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Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside Structure

Methyl 2,3-O-is...

CAS#:4137-56-8

Literature: Sairam, Pothukuchi; Puranik, Ramachandra; Sreenivasa Rao, Bhatraju; Veerabhadra Swamy, Ponnapalli; Chandra, Sharad Carbohydrate Research, 2003 , vol. 338, # 4 p. 303 - 306

~%

Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside Structure

Methyl 2,3-O-is...

CAS#:4137-56-8

Literature: Moreau, Christelle; Kirchberger, Tanja; Swarbrick, Joanna M.; Bartlett, Stephen J.; Fliegert, Ralf; Yorgan, Timur; Bauche, Andreas; Harneit, Angelika; Guse, Andreas H.; Potter, Barry V. L. Journal of Medicinal Chemistry, 2013 , vol. 56, # 24 p. 10079 - 10102

~%

Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside Structure

Methyl 2,3-O-is...

CAS#:4137-56-8

Literature: Levene; Stiller Journal of Biological Chemistry, 1934 , vol. 106, p. 421,423, 428 Full Text Show Details Barker; Spoors Journal of the Chemical Society, 1956 , p. 2656

~%

Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside Structure

Methyl 2,3-O-is...

CAS#:4137-56-8

Literature: Levene; Stiller Journal of Biological Chemistry, 1934 , vol. 106, p. 421,423, 428 Full Text Show Details Reist et al. Journal of Organic Chemistry, 1961 , vol. 26, p. 2821,2826

~40%

Detail
Literature: Stick; Stubbs; Tilbrook Australian Journal of Chemistry, 2001 , vol. 54, # 3 p. 181 - 183

 Synonyms

Methyl 2,3-O-(1-methylethylidene)-, 4-methylbenzenesulfonate-β-D-ribofuranoside
(4-methoxy-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl)methyl 4-methylbenzenesulfonate
Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-β-D-ribofuranoside
T55 BO DO GOTJ C1 C1 FO1 H1OSWR D1 &&Ribo-β-D Form
Methyl 2,3-O-isopropylidene-5-O-[(4-methylphenyl)sulfonyl]-β-D-ribofuranoside
β-D-Ribofuranoside, methyl 2,3-O-(1-methylethylidene)-, 4-methylbenzenesulfonate
MFCD00038411
Methyl 2,3-O-isopropylidene-5-O-p-toluenesulfonyl-β-D-ribofuranoside
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