(R)-Casopitant

Modify Date: 2024-01-31 13:07:48

(R)-Casopitant structure	Common Name	(R)-Casopitant
	CAS Number	414910-26-2	Molecular Weight	616.61
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₅F₇N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (R)-Casopitant

(R)-Casopitant ((R)-GW679769) is the isomer of Casopitant (HY-14405). Casopitant is a NK(1)-receptor antagonist. Casopitant can be used for the research of chemotherapy-induced nausea and vomiting[1][2].

Name	(R)-Casopitant

Description	(R)-Casopitant ((R)-GW679769) is the isomer of Casopitant (HY-14405). Casopitant is a NK(1)-receptor antagonist. Casopitant can be used for the research of chemotherapy-induced nausea and vomiting[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
References	[1]. Di Fabio, Romano, et al. Discovery and Biological Characterization of (2R,4S)-1'-Acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-4,4'-bipiperidine-1-carboxamide as a New Potent and Selective Neurokinin 1 (NK1) Receptor Antagonist Clinical Candidate. Journal of Medicinal Chemistry (2011), 54(4), 1071-1079. [2]. Christina Ruhlmann, et al. Casopitant: a novel NK(1)-receptor antagonist in the prevention of chemotherapy-induced nausea and vomiting. Ther Clin Risk Manag. 2009 Apr;5(2):375-84.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor

Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor

References

[1]. Di Fabio, Romano, et al. Discovery and Biological Characterization of (2R,4S)-1'-Acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-4,4'-bipiperidine-1-carboxamide as a New Potent and Selective Neurokinin 1 (NK1) Receptor Antagonist Clinical Candidate. Journal of Medicinal Chemistry (2011), 54(4), 1071-1079.

[2]. Christina Ruhlmann, et al. Casopitant: a novel NK(1)-receptor antagonist in the prevention of chemotherapy-induced nausea and vomiting. Ther Clin Risk Manag. 2009 Apr;5(2):375-84.

Molecular Formula	C₃₀H₃₅F₇N₄O₂
Molecular Weight	616.61

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(R)-Casopitant

Use of (R)-Casopitant

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(R)-Casopitant Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.