RDR 02308

Modify Date: 2025-08-26 14:06:03

RDR 02308 Structure
RDR 02308 structure
Common Name RDR 02308
CAS Number 4155-82-2 Molecular Weight 333.34
Density N/A Boiling Point N/A
Molecular Formula C19H15N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RDR 02308


RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase[1].

 Names

Name RDR 02308

 RDR 02308 Biological Activity

Description RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase[1].
Related Catalog
In Vitro RDR 02308 (0-10 μM; 1 h) 在 RAW264.7 细胞中抑制 LPS (HY-D1056) 介导的 IL-6 产生[1]。 Western Blot Analysis[1] Cell Line: RAW264.7 cells Concentration: 0-10 μM Incubation Time: 1 h Result: Inhibited LPS-mediated IL-6 production.
References

[1]. Lee HK, et al. Application of beta-lactamase enzyme complementation to the high-throughput screening of toll-like receptor signaling inhibitors. Mol Pharmacol. 2007 Oct;72(4):868-75.  

 Chemical & Physical Properties

Molecular Formula C19H15N3O3
Molecular Weight 333.34
InChIKey DCFSIJLWXJXSQC-UHFFFAOYSA-N
SMILES O=[N+]([O-])c1ccc(C2=NN(c3ccccc3)C(c3ccco3)C2)cc1

 RDR 02308Bioassay

View more

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Single Concentration Validation of Csn-Mediated Deneddylation of Cullin-Ring Ligase U...
Source: Burnham Center for Chemical Genomics
Target: COP9 signalosome complex subunit 5 [Homo sapiens]
External Id: SBCCG-A995-CSN5-CP-Assay
Name: Single concentration validation of Csn-Mediated Deneddylation of Cullin-Ring Ligase H...
Source: Burnham Center for Chemical Genomics
Target: 72 kDa type IV collagenase isoform a preproprotein [Homo sapiens]
External Id: SBCCG-A996-CSN5-MMP2-CP-Assay
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: HCS to Identify Inhibitors of Dynein Mediated Cargo Transport on Microtubules: Confir...
Source: University of Pittsburgh Molecular Library Screening Center
Target: N/A
External Id: HCS to Identify Inhibitors of Dynein Mediated Cargo Transport on Microtubules: Confirmation Assay, R21NS057026
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Single concentration validation of Csn-Mediated Deneddylation of Cullin-Ring Ligase U...
Source: Burnham Center for Chemical Genomics
Target: TPA: prothrombin [Bos taurus]
External Id: SBCCG-A997-CSN5-thrombin-CP-Assay
Total 110, Current Page 1 of 11
1
2
3
4
5
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.