N-(4-Nitrophenyl)-L-leucinamide
N-(4-Nitrophenyl)-L-leucinamide structure
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Common Name | N-(4-Nitrophenyl)-L-leucinamide | ||
|---|---|---|---|---|
| CAS Number | 4178-93-2 | Molecular Weight | 251.282 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 454.5±30.0 °C at 760 mmHg | |
| Molecular Formula | C12H17N3O3 | Melting Point | 88-90ºC | |
| MSDS | Chinese USA | Flash Point | 228.7±24.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | L-Leucine-p-nitroanilide |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 454.5±30.0 °C at 760 mmHg |
| Melting Point | 88-90ºC |
| Molecular Formula | C12H17N3O3 |
| Molecular Weight | 251.282 |
| Flash Point | 228.7±24.6 °C |
| Exact Mass | 251.126984 |
| PSA | 100.94000 |
| LogP | 1.83 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.589 |
| InChIKey | AXZJHDNQDSVIDR-NSHDSACASA-N |
| SMILES | CC(C)CC(N)C(=O)Nc1ccc([N+](=O)[O-])cc1 |
| Storage condition | 2-8°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317-H319 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36 |
| Safety Phrases | S26-S36-S37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2924299090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~%
N-(4-Nitropheny... CAS#:4178-93-2 |
| Literature: Okada; Tsuda; Hirata; Nagamatsu; Okamoto Chemical and pharmaceutical bulletin, 1982 , vol. 30, # 11 p. 4060 - 4068 |
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N-(4-Nitropheny... CAS#:4178-93-2 |
| Literature: Kawai, Yasushi; Matsuo, Takashi; Ohno, Atsuyoshi Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 4 p. 887 - 891 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 2 | |
|---|---|
| DownStream 4 | |
CAS#:3303-55-7
CAS#:61-90-5
CAS#:100-01-6
CAS#:14486-16-9This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum aminopeptidases, M1, M17 and M18.
PLoS ONE 10(2) , e0115859, (2015) Malaria is a parasitic disease that remains a global health burden. The ability of the parasite to rapidly develop resistance to therapeutics drives an urgent need for the delivery of new drugs. The M... |
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Beta-phenyl cysteine: a leucine aminopeptidase inhibitor.
Pharmacol. Res. Commun. 16(6) , 533-8, (1984) Beta-phenyl cysteine: a leucine aminopeptidase inhibitor. The kinetic parameters of the inhibition of the leucine aminopeptidase by beta-phenyl cysteine are reported in this communication. |
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Exploration of structural and physicochemical requirements and search of virtual hits for aminopeptidase N inhibitors.
Mol. Divers. 17(1) , 123-37, (2013) Aminopeptidase N (APN) inhibitors have been reported to be effective in treating of life threatening diseases including cancer. Validated ligand- and structure-based pharmacophore mapping approaches w... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| MFCD00063681 |
| EINECS 224-047-3 |
| N-(4-Nitrophenyl)-L-leucinamide |
| h-leu-pna |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the storage conditions for L-Leucine-p-nitroanilide? |
| A: Storage conditions for L-Leucine-p-nitroanilide: 2-8°C. |
| Q: What are the downstream products of L-Leucine-p-nitroanilide? |
| A: Related downstream products(CAS) of L-Leucine-p-nitroanilide: 3303-55-7;61-90-5;100-01-6;14486-16-9. |
| Q: What is the boiling point of L-Leucine-p-nitroanilide? |
| A: Boiling point of L-Leucine-p-nitroanilide is 454.5±30.0 °C at 760 mmHg. |
| Q: What is the safety information for L-Leucine-p-nitroanilide? |
| A: Safety information for L-Leucine-p-nitroanilide: S26-S36-S37. |
| Q: What are the upstream materials of L-Leucine-p-nitroanilide? |
| A: Related upstream materials(CAS) of L-Leucine-p-nitroanilide: 1174-27-2;114684-52-5. |
| Q: What is the molecular weight of L-Leucine-p-nitroanilide? |
| A: Molecular weight of L-Leucine-p-nitroanilide is 251.282. |
| Q: What is the melting point of L-Leucine-p-nitroanilide? |
| A: Melting point of L-Leucine-p-nitroanilide is 88-90ºC. |
| Q: What is the LogP of L-Leucine-p-nitroanilide? |
| A: LogP of L-Leucine-p-nitroanilide is 1.83. |
| Q: What is the English name of L-Leucine-p-nitroanilide? |
| A: The English name of L-Leucine-p-nitroanilide is L-Leucine-p-nitroanilide. |
| Q: What is the CAS number of L-Leucine-p-nitroanilide? |
| A: CAS number of L-Leucine-p-nitroanilide is 4178-93-2. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |