3'-Deoxy-3'-amino-ATP

Modify Date: 2024-01-16 20:12:37

3'-Deoxy-3'-amino-ATP Structure
3'-Deoxy-3'-amino-ATP structure
Common Name 3'-Deoxy-3'-amino-ATP
CAS Number 4209-30-7 Molecular Weight 506.19600
Density N/A Boiling Point N/A
Molecular Formula C10H17N6O12P3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3'-Deoxy-3'-amino-ATP


3'-Deoxy-3'-amino-ATP, an ATP analogue, is a potent and competitive inhibitor of ATP, with a Ki of 2.3 μM. 3'-Deoxy-3'-amino-ATP can be used to synthesis of 3′-Amino-3′-deoxy transfer RNA by incorporation into the 3' terminus of tRNA-C-C[1][2].

 Names

Name 3'-Deoxy-3'-amino-ATP
Synonym More Synonyms

 3'-Deoxy-3'-amino-ATP Biological Activity

Description 3'-Deoxy-3'-amino-ATP, an ATP analogue, is a potent and competitive inhibitor of ATP, with a Ki of 2.3 μM. 3'-Deoxy-3'-amino-ATP can be used to synthesis of 3′-Amino-3′-deoxy transfer RNA by incorporation into the 3' terminus of tRNA-C-C[1][2].
Related Catalog
In Vitro 3'-Deoxy-3'-amino-ATP can be used as a substrate to synthesis of 3′-Amino-3′-deoxy transfer RNA[2].
References

[1]. Armstrong VW, et, al. Interaction of substrate analogues with Escherichia coli DNA-dependent RNA polymerase. Eur J Biochem. 1976 Nov 1;70(1):33-8.

[2]. Fraser TH, et, al. Synthesis and aminoacylation of 3'-amino-3'-deoxy transfer RNA and its activity in ribosomal protein synthesis. Proc Natl Acad Sci U S A. 1973 Sep;70(9):2671-5.

 Chemical & Physical Properties

Molecular Formula C10H17N6O12P3
Molecular Weight 506.19600
Exact Mass 506.01200
PSA 314.35000

 Synonyms

3'-Amino-3'-deoxy-ATP
3'-Amino-3'-desoxyadenosin-5'-triphosphat
3'-Amino-3'-deoxyadenosine 5'-triphosphate
3'-deoxy-3'-aminoadenosine 5'-triphosphate
O5'-(tetrahydroxy-[1]triphosphoryl)-3'-amino-3'-deoxy-adenosine