Carnidazole

Modify Date: 2024-01-06 08:08:18

Carnidazole Structure
Carnidazole structure
Common Name Carnidazole
CAS Number 42116-76-7 Molecular Weight 244.271
Density 1.4±0.1 g/cm3 Boiling Point 422.8±51.0 °C at 760 mmHg
Molecular Formula C8H12N4O3S Melting Point N/A
MSDS Chinese USA Flash Point 209.5±30.4 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Use of Carnidazole


Carnidazole is an antiprotozoal agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection[1].

 Names

Name O-methyl N-[2-(2-methyl-5-nitroimidazol-1-yl)ethyl]carbamothioate
Synonym More Synonyms

 Carnidazole Biological Activity

Description Carnidazole is an antiprotozoal agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection[1].
Related Catalog
Target

Antiprotozoal[1]

References

[1]. A Notowicz, et al. First Experiences With Single-Dose Treatment of Vaginal Trichomoniasis With Carnidazole (R 25831). Br J Vener Dis. 1977 Apr;53(2):129-31.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 422.8±51.0 °C at 760 mmHg
Molecular Formula C8H12N4O3S
Molecular Weight 244.271
Flash Point 209.5±30.4 °C
Exact Mass 244.063004
PSA 116.99000
LogP 0.72
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.627
Storage condition -20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FD3912000
CHEMICAL NAME :
Carbamothioic acid, (2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl)-, O-methyl ester
CAS REGISTRY NUMBER :
42116-76-7
BEILSTEIN REFERENCE NO. :
0620260
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H12-N4-O3-S
MOLECULAR WEIGHT :
244.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
213 umol/L
REFERENCE :
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 3,51,1983

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H317-H318
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes C
RIDADR NONH for all modes of transport
RTECS FD3912000
HS Code 2933290090

 Customs

HS Code 2933290090
Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles6

More Articles
Determination of the antitubercular drug PA-824 in rat plasma, lung and brain tissues by liquid chromatography tandem mass spectrometry: application to a pharmacokinetic study.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 988 , 187-94, (2015)

A selective, sensitive and high performance liquid chromatography-tandem mass spectrometry (LC-(ESI)MS/MS) method has been developed and validated for the quantification of the potent antitubercular d...

In vitro nitroimidazole resistance of Trichomonas gallinae and successful therapy with an increased dosage of ronidazole in racing pigeons (Columba livia domestica).

J. Vet. Pharmacol. Ther. 15(4) , 409-15, (1992)

Six out of eight different Trichomonas gallinae strains isolated from racing pigeons proved to be resistant to the nitroimidazole drugs ronidazole, carnidazole and metronidazole. The minimal cytocidal...

Structural characterization of drugs and oxygenated metabolites by laser microprobe mass spectrometry (LAMMA).

Biomed. Environ. Mass Spectrom. 16(1-12) , 121-9, (1988)

Laser microprobe mass analysis (LAMMA) was used for the structural characterization of polyfunctional drugs and their oxygenated metabolites, in particular the N-oxides. The spectra usually yield the ...

 Synonyms

ME 108
Spartrix
Carnidazole
[2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl]carbamothioic Acid O-Methyl Ester
Carbamothioic acid, N-[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]-, O-methyl ester
O-Methyl [2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]carbamothioate
EINECS 255-663-0
UNII-RH5KI819JG
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