N-Methyl-N-nitrosotoluene-4-sulfonamide-d3

Modify Date: 2024-01-06 19:11:39

N-Methyl-N-nitrosotoluene-4-sulfonamide-d3 Structure
N-Methyl-N-nitrosotoluene-4-sulfonamide-d3 structure
Common Name N-Methyl-N-nitrosotoluene-4-sulfonamide-d3
CAS Number 42366-72-3 Molecular Weight 217.260
Density 1.3±0.1 g/cm3 Boiling Point 320.5±35.0 °C at 760 mmHg
Molecular Formula C8H7D3N2O3S Melting Point 60-63ºC
MSDS USA Flash Point 147.6±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of N-Methyl-N-nitrosotoluene-4-sulfonamide-d3


N-Methyl-N-nitrosotoluene-4-sulfonamide-d3 is the deuterium labeled N-Methyl-N-nitrosotoluene-4-sulfonamide[1].

 Names

Name diazald(r)-n-methyl-d3
Synonym More Synonyms

  Biological Activity

Description N-Methyl-N-nitrosotoluene-4-sulfonamide-d3 is the deuterium labeled N-Methyl-N-nitrosotoluene-4-sulfonamide[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 320.5±35.0 °C at 760 mmHg
Melting Point 60-63ºC
Molecular Formula C8H7D3N2O3S
Molecular Weight 217.260
Flash Point 147.6±25.9 °C
Exact Mass 217.060043
PSA 75.19000
LogP 0.58
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.573

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H317-H319-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Hazard Codes Xn
Risk Phrases 20/21/22-43
Safety Phrases 26-36
RIDADR UN3234 - UN3224 DOT class 4.1 (N-Methyl-N-nitroso-p-methylbenzenesulfonamide) Self-reactive solid type C, temperature controlled)

 Synonyms

4-methylcyclohexyl p-toluenesulfonate
p-Toluolsulfonsaeure-<nitroso-deuteromethylamid>
diazald-N-methyl-d3
MFCD00074893
4-Methyl-N-(H)methyl-N-nitrosobenzenesulfonamide
4-methylcyclohexyl 4-methylbenzenesulfonate
cyclohexanol,4-methyl-,4-methylbenzenesulfonate
Benzenesulfonic acid, 4-methyl-, 1-(methyl-d)-2-oxohydrazide